Ocrevus and Folate deficiency - a phase IV clinical study of FDA data

Summary:

Folate deficiency is reported as a side effect among people who take Ocrevus (ocrelizumab), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Albuterol, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Folate deficiency when taking Ocrevus. It is created by eHealthMe based on reports of 56,539 people who have side effects when taking Ocrevus from the FDA, and is updated regularly.

What is Ocrevus?

Ocrevus has active ingredients of ocrelizumab. eHealthMe is studying from 56,583 Ocrevus users. Check the latest studies of Ocrevus.

What is Folate deficiency?

Folate deficiency (lack of folic acid) is found to be associated with 223 drugs and 404 conditions by eHealthMe. Check the latest studies of Folate deficiency.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

56,539 people reported to have side effects when taking Ocrevus.
Among them, 51 people (0.09%) have Folate deficiency.

Among these 51 people:

How long have people been on Ocrevus when they have Folate deficiency? *

What is the gender of people who have Folate deficiency when taking Ocrevus? *

female: 98 %
male: 2 %

What is the age of people who have Folate deficiency when taking Ocrevus? *

What are other drugs people take besides Ocrevus? *

Albuterol: 25 people, 49.02%
Folic Acid: 21 people, 41.18%
Pantoprazole: 19 people, 37.25%
Ibuprofen: 17 people, 33.33%
Oxycodone: 17 people, 33.33%
Triamcinolone Acetonide: 16 people, 31.37%
Nitrofurantoin: 13 people, 25.49%
Ramipril: 8 people, 15.69%
Heparin: 8 people, 15.69%
Formoterol Fumarate: 8 people, 15.69%

What are other side effects people have besides Folate deficiency? *

Nasopharyngitis (inflammation of the nasopharynx): 37 people, 72.55%
Fatigue (feeling of tiredness): 32 people, 62.75%
Weakness: 30 people, 58.82%
Cystitis Noninfective (non-infectious inflammation of the wall of the bladder): 30 people, 58.82%
Fall: 26 people, 50.98%
Oral Herpes (viral infection of mouth): 25 people, 49.02%
Chills (felling of cold): 24 people, 47.06%
Pain: 23 people, 45.10%
Rashes (redness): 22 people, 43.14%
Throat Irritation: 21 people, 41.18%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 49 people, 96.08%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 17 people, 33.33%
Urinary Tract Infection: 7 people, 13.73%
Nasopharyngitis (inflammation of the nasopharynx): 7 people, 13.73%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 6 people, 11.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 9.80%
Depression: 5 people, 9.80%
Progressive Relapsing Multiple Sclerosis (chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord or both): 5 people, 9.80%
Nausea (feeling of having an urge to vomit): 4 people, 7.84%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 7.84%

* Approximation only. Some reports may have incomplete information.

Do you take Ocrevus and have Folate deficiency?

- Check whether Folate deficiency is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ocrevus:

Ocrevus (56,583 reports)

Browse all side effects of Ocrevus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Folate deficiency:

Folate deficiency (223 drugs)

Browse all the conditions that are associated with Folate deficiency:

Folate deficiency (404 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ocrelizumab (the active ingredients of Ocrevus) and Ocrevus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.