Ofirmev and Cholestasis - a phase IV clinical study of FDA data

Summary:

Cholestasis is reported as a side effect among people who take Ofirmev (acetaminophen), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Paracetamol, and have Lung disorder.

The phase IV clinical study analyzes which people have Cholestasis when taking Ofirmev. It is created by eHealthMe based on reports of 817 people who have side effects when taking Ofirmev from the FDA, and is updated regularly.

What is Ofirmev?

Ofirmev has active ingredients of acetaminophen. eHealthMe is studying from 817 Ofirmev users. Check the latest studies of Ofirmev.

What is Cholestasis?

Cholestasis (a condition where bile cannot flow from the liver to the duodenum) is found to be associated with 1,034 drugs and 1,808 conditions by eHealthMe. Check the latest studies of Cholestasis.

On Jul, 10, 2026

817 people reported to have side effects when taking Ofirmev.
Among them, 12 people (1.47%) have Cholestasis.

Among these 12 people:

How long have people been on Ofirmev when they have Cholestasis? *

What is the gender of people who have Cholestasis when taking Ofirmev? *

female: 50 %
male: 50 %

What is the age of people who have Cholestasis when taking Ofirmev? *

What are other drugs people take besides Ofirmev? *

What are other side effects people have besides Cholestasis? *

Hepatocellular Injury (liver injury): 6 people, 50.00%
Cell Death: 2 people, 16.67%
Transaminases Increased: 1 person, 8.33%
Gamma-Glutamyltransferase Increased: 1 person, 8.33%
Blood Bilirubin Increased: 1 person, 8.33%
Death: 1 person, 8.33%
Device Occlusion: 1 person, 8.33%
Encephalitis (inflammation of the brain): 1 person, 8.33%
Eosinophilia (eosinophil count in the peripheral blood exceeds): 1 person, 8.33%
Erythema Multiforme (a type of hypersensitivity reaction): 1 person, 8.33%

What are the existing conditions these people have? *

Lung Disorder (lung disease): 2 people, 16.67%
Prostate Cancer Metastatic: 1 person, 8.33%
Pain: 1 person, 8.33%
Fever: 1 person, 8.33%
Enlarged Prostate: 1 person, 8.33%
Dehydration (dryness resulting from the removal of water): 1 person, 8.33%
Behcet's Syndrome (involves inflammation of the blood vessels): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ofirmev and have Cholestasis?

- Check whether Cholestasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ofirmev:

Ofirmev (817 reports)

Cholestasis treatments and more:

Cholestasis (23,731 reports)

Browse all side effects of Ofirmev:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cholestasis:

Cholestasis (1,034 drugs)

Browse all the conditions that are associated with Cholestasis:

Cholestasis (1,808 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Ofirmev) and Ofirmev (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.