Omeprazole and Brain death - a phase IV clinical study of FDA data

Summary:

Brain death is reported as a side effect among people who take Omeprazole (omeprazole), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Amlodipine, and have Atrial fibrillation/flutter.

The study is created by eHealthMe based on reports of 400,982 people who have side effects when taking Omeprazole from the FDA, and is updated regularly.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

On Jul, 08, 2026

400,982 people reported to have side effects when taking Omeprazole.
Among them, 55 people (0.01%) died.

Among these 55 people:

How long have people been on Omeprazole when they died? *

What is the gender of people who died when taking Omeprazole? *

female: 43.14 %
male: 56.86 %

What is the age of people who died when taking Omeprazole? *

What are other drugs people take besides Omeprazole? *

What are other side effects people have before they died? *

Cardiac Arrest: 17 people, 30.91%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 10 people, 18.18%
Pneumonia: 9 people, 16.36%
Hyperkalemia (damage to or disease of the kidney): 8 people, 14.55%
Consciousness - Decreased: 8 people, 14.55%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 12.73%
Septic Shock (shock due to blood infection): 7 people, 12.73%
Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 12.73%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 10.91%
Headache (pain in head): 6 people, 10.91%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 5 people, 9.09%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 9.09%
Fungal Abscess Central Nervous System (collection of pus in brain by result of fungal infection): 4 people, 7.27%
High Blood Pressure: 4 people, 7.27%
Pain: 4 people, 7.27%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 7.27%
Localised Oedema (fluid retention in a particular part of the body): 3 people, 5.45%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 5.45%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 5.45%
Immunodeficiency Disorders: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Omeprazole:

Omeprazole (410,631 reports)

Expand to all the drugs that have ingredients of omeprazole:

Brain death and drugs with ingredients of omeprazole

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain death:

Brain death (320 drugs)

Browse all the conditions that are associated with Brain death:

Brain death (489 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole (the active ingredients of Omeprazole) and Omeprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.