Omeprazole and Corneal opacity - a phase IV clinical study of FDA data

Summary:

Corneal opacity is reported as a side effect among people who take Omeprazole (omeprazole), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Tamsulosin, and have Enlarged prostate.

The phase IV clinical study analyzes which people have Corneal opacity when taking Omeprazole. It is created by eHealthMe based on reports of 400,982 people who have side effects when taking Omeprazole from the FDA, and is updated regularly.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

What is Corneal opacity?

Corneal opacity (scarring or clouding of the cornea) is found to be associated with 126 drugs and 316 conditions by eHealthMe. Check the latest studies of Corneal opacity.



On Aug, 11, 2026

400,982 people reported to have side effects when taking Omeprazole.
Among them, 24 people (0.01%) have Corneal opacity.

Could Omeprazole cause Corneal opacity?

Among these 24 people:

How long have people been on Omeprazole when they have Corneal opacity? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Corneal opacity when taking Omeprazole? *

  • female: 36.36 %
  • male: 63.64 %

What is the age of people who have Corneal opacity when taking Omeprazole? *

  • 0-1: 20 %
  • 2-9: 5 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 0.0 %
  • 60+: 65 %

What are other drugs people take besides Omeprazole? *

  1. Tamsulosin: 7 people, 29.17%
  2. Metoclopramide: 5 people, 20.83%
  3. Azopt: 5 people, 20.83%
  4. Folic Acid: 5 people, 20.83%
  5. Pred Forte: 4 people, 16.67%
  6. Nevanac: 4 people, 16.67%
  7. Aspirin: 4 people, 16.67%
  8. Travatan: 4 people, 16.67%
  9. Carafate: 3 people, 12.50%
  10. Premarin: 3 people, 12.50%

What are other side effects people have besides Corneal opacity? *

  1. Visual Acuity Reduced (reduced clearness of vision): 7 people, 29.17%
  2. Papilloedema (optic disc swelling): 5 people, 20.83%
  3. Blindness: 4 people, 16.67%
  4. Ulcerative Keratitis (ulcerative inflammation of the cornea): 4 people, 16.67%
  5. Eye Pain: 4 people, 16.67%
  6. Corneal Disorder: 3 people, 12.50%
  7. Eyelid Oedema (eyelids are swollen and contain excessive fluid): 3 people, 12.50%
  8. Eye Discharge: 3 people, 12.50%
  9. Iridocyclitis (inflammation of the iris and ciliary body of the eye): 3 people, 12.50%
  10. Pneumococcal Infection (infection caused by streptococcus pneumoniae): 3 people, 12.50%

What are the existing conditions these people have? *

  1. Enlarged Prostate: 6 people, 25.00%
  2. Glaucoma (increased fluid pressure in the eye with vision loss): 5 people, 20.83%
  3. Retinopathy (acute damage to the retina of the eye): 4 people, 16.67%
  4. Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 2 people, 8.33%
  5. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 4.17%
  6. Hyperchlorhydria (gastric acid levels are higher in stomach): 1 person, 4.17%
  7. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 4.17%
  8. Depression: 1 person, 4.17%
  9. Fatigue (feeling of tiredness): 1 person, 4.17%
  10. Herpes Zoster: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Omeprazole and have Corneal opacity?

- Check whether Corneal opacity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Omeprazole:

Corneal opacity treatments and more:

How severe was Corneal opacity and when was it recovered:

Expand to all the drugs that have ingredients of omeprazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Corneal opacity:

Browse all the conditions that are associated with Corneal opacity:


How the study uses the data?

The study uses data from the FDA. It is based on omeprazole (the active ingredients of Omeprazole) and Omeprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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