Omeprazole and Migraine without aura - a phase IV clinical study of FDA data

Summary:

Migraine without aura is reported as a side effect among people who take Omeprazole (omeprazole), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Gabapentin, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Migraine without aura when taking Omeprazole. It is created by eHealthMe based on reports of 400,982 people who have side effects when taking Omeprazole from the FDA, and is updated regularly.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

What is Migraine without aura?

Migraine without aura (headache without neurological problems) is found to be associated with 93 drugs and 254 conditions by eHealthMe. Check the latest studies of Migraine without aura.

On May, 01, 2026

400,982 people reported to have side effects when taking Omeprazole.
Among them, 16 people (0.0%) have Migraine without aura.

Could Omeprazole cause Migraine without aura?

Among these 16 people:

How long have people been on Omeprazole when they have Migraine without aura? *

What is the gender of people who have Migraine without aura when taking Omeprazole? *

female: 81.25 %
male: 18.75 %

What is the age of people who have Migraine without aura when taking Omeprazole? *

What are other drugs people take besides Omeprazole? *

What are other side effects people have besides Migraine without aura? *

Tremor (trembling or shaking movements in one or more parts of your body): 9 people, 56.25%
Insomnia (sleeplessness): 7 people, 43.75%
Nausea (feeling of having an urge to vomit): 6 people, 37.50%
Chest Pain: 6 people, 37.50%
Dyspnea (difficult or laboured breathing): 6 people, 37.50%
Intervertebral Disc Degeneration (spinal disc degeneration): 5 people, 31.25%
Muscle Spasms (muscle contraction): 5 people, 31.25%
Weakness: 5 people, 31.25%
Cough: 5 people, 31.25%
Headache (pain in head): 5 people, 31.25%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 31.25%
Depression: 4 people, 25.00%
Spinal Stenosis (narrowing of spinal column): 3 people, 18.75%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 3 people, 18.75%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 18.75%
Neuritis (inflammation of nerve): 3 people, 18.75%
Neuralgia (pain in one or more nerves): 3 people, 18.75%
Muscle Aches (muscle pain): 3 people, 18.75%
Gait Disturbance: 3 people, 18.75%
Headache (pain in head): 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

Do you take Omeprazole and have Migraine without aura?

- Check whether Migraine without aura is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Omeprazole:

Omeprazole (410,631 reports)

Browse all side effects of Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Migraine without aura:

Migraine without aura (93 drugs)

Browse all the conditions that are associated with Migraine without aura:

Migraine without aura (254 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole (the active ingredients of Omeprazole) and Omeprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.