Omnicef and Clostridium difficile colitis - a phase IV clinical study of FDA data

Summary:

Clostridium difficile colitis is reported as a side effect among people who take Omnicef (cefdinir), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Flagyl, and have High blood pressure.

The phase IV clinical study analyzes which people have Clostridium difficile colitis when taking Omnicef. It is created by eHealthMe based on reports of 2,586 people who have side effects when taking Omnicef from the FDA, and is updated regularly.

What is Omnicef?

Omnicef has active ingredients of cefdinir. It is often used in sinusitis. eHealthMe is studying from 2,774 Omnicef users. Check the latest studies of Omnicef.

What is Clostridium difficile colitis?

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 1,040 drugs and 1,786 conditions by eHealthMe. Check the latest studies of Clostridium difficile colitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 26, 2026

2,586 people reported to have side effects when taking Omnicef.
Among them, 24 people (0.93%) have Clostridium difficile colitis.

Could Omnicef cause Clostridium difficile colitis?

Among these 24 people:

How long have people been on Omnicef when they have Clostridium difficile colitis? *

What is the gender of people who have Clostridium difficile colitis when taking Omnicef? *

female: 90 %
male: 10 %

What is the age of people who have Clostridium difficile colitis when taking Omnicef? *

What are other drugs people take besides Omnicef? *

What are other side effects people have besides Clostridium difficile colitis? *

Nausea And Vomiting: 6 people, 25.00%
Cough: 5 people, 20.83%
Dyspnea (difficult or laboured breathing): 5 people, 20.83%
Pulmonary Mass: 4 people, 16.67%
Nausea (feeling of having an urge to vomit): 4 people, 16.67%
Fever: 4 people, 16.67%
Pain: 4 people, 16.67%
Peripheral Swelling: 4 people, 16.67%
Headache (pain in head): 4 people, 16.67%
Heart Sounds Abnormal: 4 people, 16.67%

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 33.33%
Pain: 7 people, 29.17%
Osteopenia (a condition where bone mineral density is lower than normal): 6 people, 25.00%
Insomnia (sleeplessness): 6 people, 25.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 16.67%
Colitis (inflammation of colon): 4 people, 16.67%
Diarrhea: 3 people, 12.50%
Pneumonia: 2 people, 8.33%
Sedation: 1 person, 4.17%
Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Omnicef and have Clostridium difficile colitis?

- Check whether Clostridium difficile colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Omnicef:

Omnicef (2,774 reports)

Browse all side effects of Omnicef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,040 drugs)

Browse all the conditions that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,786 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cefdinir (the active ingredients of Omnicef) and Omnicef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.