Ondansetron and Primary sequestrum - a phase IV clinical study of FDA data

Summary:

Primary sequestrum is reported as a side effect among people who take Ondansetron (ondansetron), especially for people who are male, 60+ old, also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Primary sequestrum when taking Ondansetron. It is created by eHealthMe based on reports of 122,217 people who have side effects when taking Ondansetron from the FDA, and is updated regularly.

What is Ondansetron?

Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 122,738 Ondansetron users. Check the latest studies of Ondansetron.

What is Primary sequestrum?

Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone) is found to be associated with 598 drugs and 330 conditions by eHealthMe. Check the latest studies of Primary sequestrum.

On Jul, 15, 2026

122,217 people reported to have side effects when taking Ondansetron.
Among them, 51 people (0.04%) have Primary sequestrum.

Could Ondansetron cause Primary sequestrum?

Among these 51 people:

What is the gender of people who have Primary sequestrum when taking Ondansetron? *

female: 19.57 %
male: 80.43 %

What is the age of people who have Primary sequestrum when taking Ondansetron? *

What are other drugs people take besides Ondansetron? *

What are other side effects people have besides Primary sequestrum? *

Osteonecrosis Of Jaw (death of bone of jaw): 47 people, 92.16%
Pain: 42 people, 82.35%
Stress And Anxiety: 41 people, 80.39%
Fatigue (feeling of tiredness): 39 people, 76.47%
Fever: 34 people, 66.67%
Weakness: 34 people, 66.67%
Insomnia (sleeplessness): 33 people, 64.71%
Bone Disorder: 33 people, 64.71%
Osteomyelitis (infection of bone): 33 people, 64.71%
Diarrhea: 33 people, 64.71%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 28 people, 54.90%
Metastases To Bone (cancer spreads to bone): 26 people, 50.98%
High Blood Pressure: 23 people, 45.10%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 19 people, 37.25%
Pain: 17 people, 33.33%
Stress And Anxiety: 16 people, 31.37%
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 15 people, 29.41%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 15 people, 29.41%
Neoplasm Malignant (cancer tumour): 12 people, 23.53%
Insomnia (sleeplessness): 9 people, 17.65%

* Approximation only. Some reports may have incomplete information.

Do you take Ondansetron and have Primary sequestrum?

- Check whether Primary sequestrum is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ondansetron:

Ondansetron (122,738 reports)

Browse all side effects of Ondansetron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Primary sequestrum:

Primary sequestrum (598 drugs)

Browse all the conditions that are associated with Primary sequestrum:

Primary sequestrum (330 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ondansetron (the active ingredients of Ondansetron) and Ondansetron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.