Ondansetron and Serum sickness - a phase IV clinical study of FDA data

Summary:

Serum sickness is reported as a side effect among people who take Ondansetron (ondansetron), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Bendamustine, and have High blood pressure.

The phase IV clinical study analyzes which people have Serum sickness when taking Ondansetron. It is created by eHealthMe based on reports of 122,217 people who have side effects when taking Ondansetron from the FDA, and is updated regularly.

What is Ondansetron?

Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 122,738 Ondansetron users. Check the latest studies of Ondansetron.

What is Serum sickness?

Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum) is found to be associated with 273 drugs and 488 conditions by eHealthMe. Check the latest studies of Serum sickness.



On Jul, 13, 2026

122,217 people reported to have side effects when taking Ondansetron.
Among them, 26 people (0.02%) have Serum sickness.

Could Ondansetron cause Serum sickness?

Among these 26 people:

How long have people been on Ondansetron when they have Serum sickness? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Serum sickness when taking Ondansetron? *

  • female: 10 %
  • male: 90 %

What is the age of people who have Serum sickness when taking Ondansetron? *

  • 0-1: 0.0 %
  • 2-9: 15 %
  • 10-19: 5 %
  • 20-29: 10 %
  • 30-39: 0.0 %
  • 40-49: 5 %
  • 50-59: 10 %
  • 60+: 55 %

What are other drugs people take besides Ondansetron? *

  1. Bendamustine: 9 people, 34.62%
  2. Truxima: 7 people, 26.92%
  3. Bactrim: 6 people, 23.08%
  4. Acetaminophen: 5 people, 19.23%
  5. Clonidine: 4 people, 15.38%
  6. Gabapentin: 4 people, 15.38%
  7. Risperidone: 3 people, 11.54%
  8. Amlodipine: 3 people, 11.54%
  9. Cefazolin: 3 people, 11.54%
  10. Celecoxib: 3 people, 11.54%

What are other side effects people have besides Serum sickness? *

  1. Back Pain: 5 people, 19.23%
  2. Fatigue (feeling of tiredness): 5 people, 19.23%
  3. Hypotension (abnormally low blood pressure): 5 people, 19.23%
  4. Drug Specific Antibody Present: 3 people, 11.54%
  5. Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 3 people, 11.54%
  6. Opsoclonus Myoclonus (a rare neurological disorder of unknown causes which appears to be the result of an autoimmune process involving the nervous system): 3 people, 11.54%
  7. Diarrhea: 2 people, 7.69%
  8. Blood Creatinine Increased: 2 people, 7.69%
  9. Joint Pain: 2 people, 7.69%
  10. Fever: 2 people, 7.69%

What are the existing conditions these people have? *

  1. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 6 people, 23.08%
  2. High Blood Pressure: 6 people, 23.08%
  3. Nodal Marginal Zone B-Cell Lymphoma Stage Iv (a type of blood cancer has spread beyond the lymph nodes to other organs, such as the bones, liver or lungs): 4 people, 15.38%
  4. Lymphoma (cancer that begins in immune system cells): 4 people, 15.38%
  5. Opsoclonus Myoclonus (a rare neurological disorder of unknown causes which appears to be the result of an autoimmune process involving the nervous system): 3 people, 11.54%
  6. Neuropathy Peripheral (surface nerve damage): 1 person, 3.85%
  7. Muscle Disorder (muscle disease): 1 person, 3.85%
  8. Muscle Aches (muscle pain): 1 person, 3.85%
  9. Migraine (headache): 1 person, 3.85%
  10. Swallowing Difficulty: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Ondansetron and have Serum sickness?

- Check whether Serum sickness is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ondansetron:

Serum sickness treatments and more:

How severe was Serum sickness and when was it recovered:

Expand to all the drugs that have ingredients of ondansetron:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ondansetron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Serum sickness:

Browse all the conditions that are associated with Serum sickness:


How the study uses the data?

The study uses data from the FDA. It is based on ondansetron (the active ingredients of Ondansetron) and Ondansetron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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