Onpattro and Urinary tract infection - a phase IV clinical study of FDA data

Summary:

Urinary tract infection is reported as a side effect among people who take Onpattro (patisiran), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Hereditary neuropathic amyloidosis.

The phase IV clinical study analyzes which people have Urinary tract infection when taking Onpattro. It is created by eHealthMe based on reports of 2,785 people who have side effects when taking Onpattro from the FDA, and is updated regularly.

What is Onpattro?

Onpattro has active ingredients of patisiran. eHealthMe is studying from 2,785 Onpattro users. Check the latest studies of Onpattro.

What is Urinary tract infection?

Urinary tract infection is found to be associated with 3,013 drugs and 3,955 conditions by eHealthMe. Check the latest studies of Urinary tract infection.



On Jul, 05, 2026

2,785 people reported to have side effects when taking Onpattro.
Among them, 69 people (2.48%) have Urinary tract infection.

Could Onpattro cause Urinary tract infection?

Among these 69 people:

How long have people been on Onpattro when they have Urinary tract infection? *

  • < 1 month: 37.5 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 25.0 %
  • 1 - 2 years: 12.5 %
  • 2 - 5 years: 25.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Urinary tract infection when taking Onpattro? *

  • female: 34.48 %
  • male: 65.52 %

What is the age of people who have Urinary tract infection when taking Onpattro? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 6.67 %
  • 50-59: 13.33 %
  • 60+: 80.0 %

What are other drugs people take besides Onpattro? *

  1. Acetaminophen: 14 people, 20.29%
  2. Vitamin A: 10 people, 14.49%
  3. Vyndaqel: 6 people, 8.70%
  4. Famotidine: 6 people, 8.70%
  5. Polaramine: 6 people, 8.70%
  6. Prednisone: 6 people, 8.70%
  7. Dexamethasone: 6 people, 8.70%
  8. Lyrica: 5 people, 7.25%
  9. Hizentra: 5 people, 7.25%
  10. Gabapentin: 5 people, 7.25%

What are other side effects people have besides Urinary tract infection? *

  1. Fever: 16 people, 23.19%
  2. Fatigue (feeling of tiredness): 12 people, 17.39%
  3. Pneumonia: 11 people, 15.94%
  4. Diarrhea: 10 people, 14.49%
  5. Malaise (a feeling of general discomfort or uneasiness): 8 people, 11.59%
  6. Infusion Related Reaction: 8 people, 11.59%
  7. Hypotension (abnormally low blood pressure): 8 people, 11.59%
  8. Skin Blushing/flushing (a sudden reddening of the face, neck): 8 people, 11.59%
  9. Chills (felling of cold): 7 people, 10.14%
  10. Nausea (feeling of having an urge to vomit): 7 people, 10.14%

What are the existing conditions these people have? *

  1. Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 44 people, 63.77%
  2. Amyloidosis Senile (common form of amyloidosis in very old people, usually mild and limited to the heart): 6 people, 8.70%
  3. Amyloidosis (a tumour within which amyloid is produced): 6 people, 8.70%
  4. Immunodeficiency Common Variable: 5 people, 7.25%
  5. Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 7.25%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.80%
  7. Neuropathy Peripheral (surface nerve damage): 2 people, 2.90%
  8. Neuralgia (pain in one or more nerves): 2 people, 2.90%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 2.90%
  10. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 2 people, 2.90%

* Approximation only. Some reports may have incomplete information.

Do you take Onpattro and have Urinary tract infection?

- Check whether Urinary tract infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Onpattro:

Urinary tract infection treatments and more:

How severe was Urinary tract infection and when was it recovered:

Expand to all the drugs that have ingredients of patisiran:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Onpattro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urinary tract infection:

Browse all the conditions that are associated with Urinary tract infection:


How the study uses the data?

The study uses data from the FDA. It is based on patisiran (the active ingredients of Onpattro) and Onpattro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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