Opana and Parkinsonism aggravated - a phase IV clinical study of FDA data

Summary:

Parkinsonism aggravated is reported as a side effect among people who take Opana (oxymorphone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Oxycontin, and have Narcolepsy.

The phase IV clinical study analyzes which people have Parkinsonism aggravated when taking Opana. It is created by eHealthMe based on reports of 39,845 people who have side effects when taking Opana from the FDA, and is updated regularly.

What is Opana?

Opana has active ingredients of oxymorphone hydrochloride. It is often used in pain. eHealthMe is studying from 40,340 Opana users. Check the latest studies of Opana.

What is Parkinsonism aggravated?

Parkinsonism aggravated (a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination) is found to be associated with 1,023 drugs and 344 conditions by eHealthMe. Check the latest studies of Parkinsonism aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

39,845 people reported to have side effects when taking Opana.
Among them, 14 people (0.04%) have Parkinsonism aggravated.

Could Opana cause Parkinsonism aggravated?

Among these 14 people:

How long have people been on Opana when they have Parkinsonism aggravated? *

What is the gender of people who have Parkinsonism aggravated when taking Opana? *

female: 61.54 %
male: 38.46 %

What is the age of people who have Parkinsonism aggravated when taking Opana? *

What are other drugs people take besides Opana? *

What are other side effects people have besides Parkinsonism aggravated? *

Fall: 6 people, 42.86%
Depression: 5 people, 35.71%
Memory Loss: 5 people, 35.71%
Drug Dependence: 4 people, 28.57%
Diabetes: 3 people, 21.43%
Fever: 3 people, 21.43%
Muscle Spasms (muscle contraction): 3 people, 21.43%
Nausea And Vomiting: 3 people, 21.43%
Disability: 3 people, 21.43%
Infection: 3 people, 21.43%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 21.43%
Breakthrough Pain: 2 people, 14.29%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 7.14%
Hypersensitivity: 1 person, 7.14%
Gastroparesis (delayed emptying of food from the stomach): 1 person, 7.14%
Abdominal Discomfort: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Opana and have Parkinsonism aggravated?

- Check whether Parkinsonism aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Opana:

Opana (40,340 reports)

Browse all side effects of Opana:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Parkinsonism aggravated:

Parkinsonism aggravated (1,023 drugs)

Browse all the conditions that are associated with Parkinsonism aggravated:

Parkinsonism aggravated (344 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxymorphone hydrochloride (the active ingredients of Opana) and Opana (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.