Trusopt and Stroke - a phase IV clinical study of FDA data


Stroke is found among people who take Trusopt, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Trusopt and have Stroke. It is created by eHealthMe based on reports of 2,956 people who have side effects when taking Trusopt from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 03, 2023

2,956 people reported to have side effects when taking Trusopt.
Among them, 38 people (1.29%) have Stroke.

What is Trusopt?

Trusopt has active ingredients of dorzolamide hydrochloride. It is often used in glaucoma. eHealthMe is studying from 2,997 Trusopt users for its effectiveness, alternative drugs and more.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 3,436 drugs and 2,911 conditions by eHealthMe.

Number of Trusopt and Stroke reports submitted per year:

Could Trusopt cause Stroke?

Time on Trusopt when people have Stroke *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Stroke when taking Trusopt *:

  • female: 51.35 %
  • male: 48.65 %

Age of people who have Stroke when taking Trusopt *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 13.33 %
  • 50-59: 3.33 %
  • 60+: 83.33 %

Common drugs people take besides Trusopt *:

  1. Lasix: 17 people, 44.74%
  2. Vioxx: 14 people, 36.84%
  3. Xalatan: 13 people, 34.21%
  4. Zocor: 12 people, 31.58%
  5. Vasotec: 9 people, 23.68%
  6. Synthroid: 7 people, 18.42%
  7. Alphagan: 7 people, 18.42%
  8. Norvasc: 6 people, 15.79%
  9. Spiriva: 6 people, 15.79%
  10. Diovan: 5 people, 13.16%

Common side effects people have besides Stroke *:

  1. High Blood Pressure: 15 people, 39.47%
  2. Lacunar Infarction (type of stroke): 11 people, 28.95%
  3. Injury: 11 people, 28.95%
  4. Stable Angina (a constant chest pain): 11 people, 28.95%
  5. Stress And Anxiety: 10 people, 26.32%
  6. Cardiac Failure Congestive: 10 people, 26.32%
  7. Productive Cough: 10 people, 26.32%
  8. Muscle Aches (muscle pain): 10 people, 26.32%
  9. Muscle Cramps (painful sensations caused by muscle contraction): 10 people, 26.32%
  10. Nosebleed (bleeding from nose): 10 people, 26.32%

Common conditions people have *:

  1. Exostosis (formation of new bone on the surface of a bone): 6 people, 15.79%
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 15.79%
  3. Stress And Anxiety: 5 people, 13.16%
  4. Metastases To Central Nervous System (cancer spreads to central nervous system): 5 people, 13.16%
  5. Bone Disorder: 2 people, 5.26%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.26%
  7. High Blood Pressure: 2 people, 5.26%
  8. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 2.63%
  9. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 2.63%
  10. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Trusopt and have Stroke?

Check whether Stroke is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Stroke and when was it recovered:

Expand to all the drugs that have ingredients of dorzolamide hydrochloride:

Alternative drugs to, pros and cons of Trusopt:

Common Trusopt side effects:

Browse all side effects of Trusopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Stroke treatments and more:

COVID vaccines that are related to Stroke:

Common drugs associated with Stroke:

All the drugs that are associated with Stroke:

Common conditions associated with Stroke:

All the conditions that are associated with Stroke:

How the study uses the data?

The study uses data from the FDA. It is based on dorzolamide hydrochloride (the active ingredients of Trusopt) and Trusopt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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