Osphena and Weakness - a phase IV clinical study of FDA data

Summary:

Weakness is reported as a side effect among people who take Osphena (ospemifene), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Sulfamethoxazole And Trimethoprim, and have Vulvovaginal dryness.

The phase IV clinical study analyzes which people have Weakness when taking Osphena. It is created by eHealthMe based on reports of 2,741 people who have side effects when taking Osphena from the FDA, and is updated regularly.

What is Osphena?

Osphena has active ingredients of ospemifene. eHealthMe is studying from 2,762 Osphena users. Check the latest studies of Osphena.

What is Weakness?

Weakness is found to be associated with 3,641 drugs and 6,612 conditions by eHealthMe. Check the latest studies of Weakness.

On Jul, 13, 2026

2,741 people reported to have side effects when taking Osphena.
Among them, 40 people (1.46%) have Weakness.

Among these 40 people:

How long have people been on Osphena when they have Weakness? *

What is the gender of people who have Weakness when taking Osphena? *

female: 100 %
male: 0.0 %

What is the age of people who have Weakness when taking Osphena? *

What are other drugs people take besides Osphena? *

Crestor: 5 people, 12.50%
Sulfamethoxazole And Trimethoprim: 5 people, 12.50%
Estrace: 4 people, 10.00%
Pepcid: 4 people, 10.00%
Methocarbamol: 4 people, 10.00%
Gabapentin: 4 people, 10.00%
Ampyra: 4 people, 10.00%
Vitamin D3: 4 people, 10.00%
Diflucan: 3 people, 7.50%
Levothyroxine Sodium: 3 people, 7.50%

What are other side effects people have besides Weakness? *

Fatigue (feeling of tiredness): 13 people, 32.50%
Muscle Spasms (muscle contraction): 12 people, 30.00%
Dyspnea (difficult or laboured breathing): 9 people, 22.50%
Drowsiness: 8 people, 20.00%
Headache (pain in head): 8 people, 20.00%
Gait Disturbance: 8 people, 20.00%
Hypoaesthesia (reduced sense of touch or sensation): 7 people, 17.50%
Dizziness: 7 people, 17.50%
Hyperhidrosis (abnormally increased sweating): 6 people, 15.00%
Nausea (feeling of having an urge to vomit): 6 people, 15.00%

What are the existing conditions these people have? *

Vulvovaginal Dryness: 11 people, 27.50%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 17.50%
Sexual Intercourse - Painful: 7 people, 17.50%
Atrophic Vulvovaginitis (inflammation of the vulva): 5 people, 12.50%
Osteoporosis (bones weak and more likely to break): 3 people, 7.50%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 3 people, 7.50%
Optic Neuritis (optic nerve inflammation): 2 people, 5.00%
High Blood Pressure: 2 people, 5.00%
Pain: 2 people, 5.00%
Itching: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Osphena and have Weakness?

- Check whether Weakness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Osphena:

Osphena (2,762 reports)

Weakness treatments and more:

Weakness (586,876 reports)

Browse all side effects of Osphena:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weakness:

Weakness (3,641 drugs)

Browse all the conditions that are associated with Weakness:

Weakness (6,612 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ospemifene (the active ingredients of Osphena) and Osphena (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.