Otezla and Haematuria - a phase IV clinical study of FDA data

Summary:

Haematuria is reported as a side effect among people who take Otezla (apremilast), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Cosentyx, and have Psoriasis.

The phase IV clinical study analyzes which people have Haematuria when taking Otezla. It is created by eHealthMe based on reports of 146,032 people who have side effects when taking Otezla from the FDA, and is updated regularly.

What is Otezla?

Otezla has active ingredients of apremilast. It is often used in psoriatic arthritis. eHealthMe is studying from 146,254 Otezla users. Check the latest studies of Otezla.

What is Haematuria?

Haematuria (presence of blood in urine) is found to be associated with 1,694 drugs and 2,527 conditions by eHealthMe. Check the latest studies of Haematuria.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

146,032 people reported to have side effects when taking Otezla.
Among them, 36 people (0.02%) have Haematuria.

Among these 36 people:

How long have people been on Otezla when they have Haematuria? *

What is the gender of people who have Haematuria when taking Otezla? *

female: 44.12 %
male: 55.88 %

What is the age of people who have Haematuria when taking Otezla? *

What are other drugs people take besides Otezla? *

What are other side effects people have besides Haematuria? *

Diarrhea: 10 people, 27.78%
Urinary Tract Infection: 6 people, 16.67%
Urination - Painful: 5 people, 13.89%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 3 people, 8.33%
Joint Pain: 3 people, 8.33%
Constipation: 3 people, 8.33%
Nausea And Vomiting: 3 people, 8.33%
Bladder Cancer Recurrent: 3 people, 8.33%
Bladder Cancer: 3 people, 8.33%
Nausea (feeling of having an urge to vomit): 3 people, 8.33%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 28 people, 77.78%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 7 people, 19.44%
High Blood Pressure: 5 people, 13.89%
Insomnia (sleeplessness): 3 people, 8.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.56%
Cardiac Disorder: 2 people, 5.56%
Depression: 2 people, 5.56%
Gastritis - Chronic (long lasting inflammation of stomach): 2 people, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.56%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Otezla and have Haematuria?

- Check whether Haematuria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Otezla:

Otezla (146,254 reports)

Haematuria treatments and more:

Haematuria (44,248 reports)

Browse all side effects of Otezla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haematuria:

Haematuria (1,694 drugs)

Browse all the conditions that are associated with Haematuria:

Haematuria (2,527 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on apremilast (the active ingredients of Otezla) and Otezla (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.