Oxycodone and acetaminophen and Injection site bruising - a phase IV clinical study of FDA data

Summary:

Injection site bruising is reported as a side effect among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride), especially for people who are female, 60+ old, also take Vitamin D3, and have Asthma.

The phase IV clinical study analyzes which people have Injection site bruising when taking Oxycodone and acetaminophen. It is created by eHealthMe based on reports of 13,404 people who have side effects when taking Oxycodone and acetaminophen from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Injection site bruising?

Injection site bruising is found to be associated with 1,064 drugs and 1,051 conditions by eHealthMe. Check the latest studies of Injection site bruising.

On Jul, 11, 2026

13,404 people reported to have side effects when taking Oxycodone and acetaminophen.
Among them, 38 people (0.28%) have Injection site bruising.

Could Oxycodone and acetaminophen cause Injection site bruising?

Among these 38 people:

What is the gender of people who have Injection site bruising when taking Oxycodone and acetaminophen? *

female: 94.12 %
male: 5.88 %

What is the age of people who have Injection site bruising when taking Oxycodone and acetaminophen? *

What are other drugs people take besides Oxycodone and acetaminophen? *

Vitamin D3: 10 people, 26.32%
Kadian: 7 people, 18.42%
Symbicort: 7 people, 18.42%
Qvar: 6 people, 15.79%
Ondansetron Hydrochloride: 6 people, 15.79%
Oxycodone Hydrochloride: 6 people, 15.79%
Singulair: 6 people, 15.79%
Cholestyramine: 5 people, 13.16%
Nifedipine: 5 people, 13.16%
Jardiance: 5 people, 13.16%

What are other side effects people have besides Injection site bruising? *

Diarrhea: 16 people, 42.11%
Hypoaesthesia (reduced sense of touch or sensation): 13 people, 34.21%
Pain In Extremity: 12 people, 31.58%
Nausea And Vomiting: 12 people, 31.58%
Weight Decreased: 12 people, 31.58%
Hypotension (abnormally low blood pressure): 12 people, 31.58%
Malaise (a feeling of general discomfort or uneasiness): 12 people, 31.58%
Joint Pain: 11 people, 28.95%
Injection Site Pain: 11 people, 28.95%
Fatigue (feeling of tiredness): 11 people, 28.95%

What are the existing conditions these people have? *

Asthma: 9 people, 23.68%
Herpes Zoster: 7 people, 18.42%
Eye Pain: 7 people, 18.42%
Facial Pain: 7 people, 18.42%
Headache (pain in head): 7 people, 18.42%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 15.79%
Pneumonia: 6 people, 15.79%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 13.16%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 7.89%
Growth Hormone Deficiency: 3 people, 7.89%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and acetaminophen and have Injection site bruising?

- Check whether Injection site bruising is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone and acetaminophen:

Oxycodone and acetaminophen (14,467 reports)

Injection site bruising treatments and more:

Injection site bruising (75,796 reports)

How severe was Injection site bruising and when was it recovered:

Injection site bruising in Oxycodone and acetaminophen

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Injection site bruising and drugs with ingredients of acetaminophen; oxycodone hydrochloride (254 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone and acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site bruising:

Injection site bruising (1,064 drugs)

Browse all the conditions that are associated with Injection site bruising:

Injection site bruising (1,051 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Oxycodone and acetaminophen) and Oxycodone and acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.