Coumadin and Curcumin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coumadin (warfarin sodium) and Curcumin (turmeric). Common drug interactions include angioedema among females and adverse drug reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Coumadin and Curcumin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

What is Curcumin?

Curcumin has active ingredients of turmeric. It is often used in inflammation. eHealthMe is studying from 3,676 Curcumin users. Check the latest studies of Curcumin.



On Jul, 11, 2026

36 people who take Coumadin and Curcumin together, and have interactions are studied.

Coumadin and Curcumin drug interactions.

What are the common drug interactions of Coumadin and Curcumin, by gender? *:

female:

  1. Angioedema (rapid swelling of the dermis)
  2. Drug hypersensitivity
  3. Pain in extremity
  4. Arthralgia (joint pain)
  5. Balance disorder
  6. Brain neoplasm (tumour of brain)
  7. Chest pain
  8. Dizziness
  9. Dry skin
  10. Dysphagia (a condition in which swallowing is difficult or painful)

male:

  1. Adverse drug reaction
  2. Bone pain
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Vomiting
  5. Abdominal distension
  6. Aspartate aminotransferase increased
  7. Muscle spasms (muscle contraction)
  8. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  9. Neuropathy peripheral (surface nerve damage)
  10. Abdominal discomfort

What are the common drug interactions of Coumadin and Curcumin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Muscle spasms (muscle contraction)
  2. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  3. Neuropathy peripheral (surface nerve damage)
  4. Bone marrow failure
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Refractory anaemia with an excess of blasts (one or more cell types are low in the blood and look abnormal in the bone marrow)

60+:

  1. Dizziness
  2. Angioedema (rapid swelling of the dermis)
  3. Presyncope
  4. Prostatic specific antigen increased
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Vomiting
  7. Abdominal distension
  8. Aspartate aminotransferase increased
  9. Fall
  10. International normalised ratio increased

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 14 people, 38.89%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 11.11%
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 11.11%
  4. Prostate Cancer Metastatic: 3 people, 8.33%
  5. Sinus Disorder (disease of sinus): 2 people, 5.56%
  6. Prostate Cancer: 2 people, 5.56%
  7. Pain: 2 people, 5.56%
  8. Lyme Disease (a bacterial infection that is spread to humans by infected ticks): 2 people, 5.56%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.56%
  10. Hyperkalemia (damage to or disease of the kidney): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Coumadin and Curcumin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Coumadin and Curcumin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Coumadin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Curcumin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Coumadin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Curcumin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on warfarin sodium and turmeric (the active ingredients of Coumadin and Curcumin, respectively), and Coumadin and Curcumin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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