Zoledronic and Zetia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoledronic (zoledronic acid) and Zetia (ezetimibe). Common drug interactions include urinary tract infection among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Zoledronic and Zetia. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

What is Zetia?

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.



On Jul, 11, 2026

39 people who take Zoledronic and Zetia together, and have interactions are studied.

Zoledronic and Zetia drug interactions.

What are the common drug interactions of Zoledronic and Zetia, by gender? *:

female:

  1. Urinary tract infection
  2. Application site erythema (redness of the skin at application site)
  3. Application site warmth
  4. Blood glucose decreased
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Compression fracture (fracture due to pressure caused by injury)
  7. Constipation
  8. Cough
  9. Diarrhoea
  10. Exposed bone in jaw

male:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Fatigue (feeling of tiredness)
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Device occlusion
  6. Diabetic complication
  7. Diarrhoea
  8. Fall
  9. Haematocrit decreased
  10. Head injury

What are the common drug interactions of Zoledronic and Zetia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Osteomyelitis (infection of bone)

50-59:

  1. Tooth infection
  2. Urinary tract infection
  3. Femur fracture
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Osteonecrosis of jaw (death of bone of jaw)
  6. Dizziness
  7. Fatigue (feeling of tiredness)
  8. Headache (pain in head)
  9. Hepatic enzyme increased
  10. Infusion related reaction

60+:

  1. Anaemia (lack of blood)
  2. Back pain
  3. Bone disorder
  4. Cardiac failure congestive
  5. Dental caries
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Facial pain
  8. Groin pain
  9. Injury
  10. Intervertebral disc disorder (spinal disc disorder)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 15 people, 38.46%
  2. Pain: 9 people, 23.08%
  3. Muscle Spasms (muscle contraction): 7 people, 17.95%
  4. Osteoporosis (bones weak and more likely to break): 2 people, 5.13%
  5. Immunodeficiency Common Variable: 2 people, 5.13%
  6. Breast Cancer: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Zoledronic and Zetia?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zoledronic and Zetia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zetia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zoledronic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zetia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid and ezetimibe (the active ingredients of Zoledronic and Zetia, respectively), and Zoledronic and Zetia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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