Oxycodone and acetaminophen and Intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Intestinal obstruction is reported as a side effect among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lisinopril, and have High blood pressure.

The phase IV clinical study analyzes which people have Intestinal obstruction when taking Oxycodone and acetaminophen. It is created by eHealthMe based on reports of 13,404 people who have side effects when taking Oxycodone and acetaminophen from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Intestinal obstruction?

Intestinal obstruction is found to be associated with 1,885 drugs and 2,619 conditions by eHealthMe. Check the latest studies of Intestinal obstruction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

13,404 people reported to have side effects when taking Oxycodone and acetaminophen.
Among them, 55 people (0.41%) have Intestinal obstruction.

Could Oxycodone and acetaminophen cause Intestinal obstruction?

Among these 55 people:

How long have people been on Oxycodone and acetaminophen when they have Intestinal obstruction? *

What is the gender of people who have Intestinal obstruction when taking Oxycodone and acetaminophen? *

female: 54.9 %
male: 45.1 %

What is the age of people who have Intestinal obstruction when taking Oxycodone and acetaminophen? *

What are other drugs people take besides Oxycodone and acetaminophen? *

What are other side effects people have besides Intestinal obstruction? *

Constipation: 15 people, 27.27%
Nausea (feeling of having an urge to vomit): 15 people, 27.27%
Weakness: 9 people, 16.36%
Stress And Anxiety: 9 people, 16.36%
Cataract (clouding of the lens inside the eye): 8 people, 14.55%
Confusional State: 8 people, 14.55%
Blood Glucose Increased: 7 people, 12.73%
Pneumonia: 7 people, 12.73%
Nausea And Vomiting: 7 people, 12.73%
Abdominal Pain Upper: 7 people, 12.73%

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 16.36%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 10.91%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.09%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 9.09%
Stress And Anxiety: 4 people, 7.27%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 7.27%
Muscle Spasms (muscle contraction): 4 people, 7.27%
Neuralgia (pain in one or more nerves): 4 people, 7.27%
Asthma: 4 people, 7.27%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 7.27%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and acetaminophen and have Intestinal obstruction?

- Check whether Intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone and acetaminophen:

Oxycodone and acetaminophen (14,467 reports)

Intestinal obstruction treatments and more:

Intestinal obstruction (59,346 reports)

How severe was Intestinal obstruction and when was it recovered:

Intestinal obstruction in Oxycodone and acetaminophen

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Intestinal obstruction and drugs with ingredients of acetaminophen; oxycodone hydrochloride (586 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone and acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal obstruction:

Intestinal obstruction (1,885 drugs)

Browse all the conditions that are associated with Intestinal obstruction:

Intestinal obstruction (2,619 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Oxycodone and acetaminophen) and Oxycodone and acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.