Oxycodone and Cell death - a phase IV clinical study of FDA data

Summary:

Cell death is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Paracetamol, and have Epilepsy.

The study is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,583 Oxycodone users. Check the latest studies of Oxycodone.

On Sep, 01, 2025

159,853 people reported to have side effects when taking Oxycodone.
Among them, 23 people (0.01%) died.

Among these 23 people:

How long have people been on Oxycodone when they died? *

What is the gender of people who died when taking Oxycodone? *

female: 72.73 %
male: 27.27 %

What is the age of people who died when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have before they died? *

Toxic Skin Eruption (skin breakdown due to toxic substance): 10 people, 43.48%
Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 9 people, 39.13%
Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 5 people, 21.74%
Gamma-Glutamyltransferase Increased: 5 people, 21.74%
Anaemia (lack of blood): 4 people, 17.39%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 3 people, 13.04%
Erythema Multiforme (a type of hypersensitivity reaction): 3 people, 13.04%
Thrombocytopenia (decrease of platelets in blood): 3 people, 13.04%
Hepatic Failure (liver failure): 3 people, 13.04%
Stomatitis (inflammation of mucous membrane of mouth): 3 people, 13.04%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 10 people, 43.48%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 10 people, 43.48%
Headache (pain in head): 5 people, 21.74%
Constipation: 5 people, 21.74%
Abdominal Pain: 5 people, 21.74%
Infection: 4 people, 17.39%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 17.39%
Bone Pain: 3 people, 13.04%
Insomnia (sleeplessness): 2 people, 8.70%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,583 reports)

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Cell death and drugs with ingredients of oxycodone hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cell death:

Cell death (263 drugs)

Browse all the conditions that are associated with Cell death:

Cell death (331 conditions)

Drugs similar to Oxycodone and Cell death :

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.