Oxycodone and Facial paralysis - a phase IV clinical study of FDA data

Summary:

Facial paralysis is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ondansetron, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Facial paralysis when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,583 Oxycodone users. Check the latest studies of Oxycodone.

What is Facial paralysis?

Facial paralysis (loss of function of face muscle) is found to be associated with 742 drugs and 1,096 conditions by eHealthMe. Check the latest studies of Facial paralysis.

On Oct, 19, 2025

159,853 people reported to have side effects when taking Oxycodone.
Among them, 78 people (0.05%) have Facial paralysis.

Among these 78 people:

How long have people been on Oxycodone when they have Facial paralysis? *

What is the gender of people who have Facial paralysis when taking Oxycodone? *

female: 58.9 %
male: 41.1 %

What is the age of people who have Facial paralysis when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Facial paralysis? *

Pain In Extremity: 26 people, 33.33%
Joint Pain: 25 people, 32.05%
Headache (pain in head): 24 people, 30.77%
Nausea (feeling of having an urge to vomit): 22 people, 28.21%
Speech Impairment (Adult) (inability to speak (adult)): 21 people, 26.92%
Hypotension (abnormally low blood pressure): 20 people, 25.64%
High Blood Pressure: 20 people, 25.64%
Fall: 20 people, 25.64%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 18 people, 23.08%
Weight Decreased: 18 people, 23.08%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 21 people, 26.92%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 7 people, 8.97%
Psoriasis (immune-mediated disease that affects the skin): 7 people, 8.97%
High Blood Pressure: 6 people, 7.69%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 6.41%
High Blood Cholesterol: 4 people, 5.13%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 5.13%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 5.13%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 5.13%
Nerve Injury: 4 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Facial paralysis?

- Check whether Facial paralysis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,583 reports)

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Facial paralysis:

Facial paralysis (742 drugs)

Browse all the conditions that are associated with Facial paralysis:

Facial paralysis (1,096 conditions)

Drugs similar to Oxycodone and Facial paralysis :

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.