Paclitaxel and Mediastinitis - a phase IV clinical study of FDA data

Summary:

Mediastinitis is reported as a side effect among people who take Paclitaxel (paclitaxel), especially for people who are female, 60+ old, also take Carboplatin, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Mediastinitis when taking Paclitaxel. It is created by eHealthMe based on reports of 85,850 people who have side effects when taking Paclitaxel from the FDA, and is updated regularly.

What is Paclitaxel?

Paclitaxel has active ingredients of paclitaxel. It is often used in breast cancer. eHealthMe is studying from 85,928 Paclitaxel users. Check the latest studies of Paclitaxel.

What is Mediastinitis?

Mediastinitis (inflammation of the tissues in the mid-chest) is found to be associated with 96 drugs and 230 conditions by eHealthMe. Check the latest studies of Mediastinitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

85,850 people reported to have side effects when taking Paclitaxel.
Among them, 18 people (0.02%) have Mediastinitis.

Among these 18 people:

What is the gender of people who have Mediastinitis when taking Paclitaxel? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Mediastinitis when taking Paclitaxel? *

What are other drugs people take besides Paclitaxel? *

Opdivo: 2 people, 11.11%
Carboplatin: 2 people, 11.11%
Yervoy: 1 person, 5.56%

What are other side effects people have besides Mediastinitis? *

Pulmonary Vein Stenosis (narrowing of lung veins): 6 people, 33.33%
Pulmonary Artery Stenosis (narrowing (stenosis) that occurs in the lung artery): 6 people, 33.33%
Infectious Pleural Effusion (infectious fluid in the lung): 2 people, 11.11%
Mediastinal Fibrosis (fibrosis of mediastinal soft tissues): 2 people, 11.11%
Disease Progression: 1 person, 5.56%
Febrile Neutropenia (fever with reduced white blood cells): 1 person, 5.56%
Fatigue (feeling of tiredness): 1 person, 5.56%
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 1 person, 5.56%
Dyspnea (difficult or laboured breathing): 1 person, 5.56%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 1 person, 5.56%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 4 people, 22.22%
Oesophageal Carcinoma (cancer tumour of oesophagus): 2 people, 11.11%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 11.11%
Breast Cancer Female: 2 people, 11.11%
Oesophageal Squamous Cell Carcinoma (cancer that begins in flat cells lining the oesophagus): 1 person, 5.56%
Disease Recurrence: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Paclitaxel and have Mediastinitis?

- Check whether Mediastinitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paclitaxel:

Paclitaxel (85,928 reports)

Mediastinitis treatments and more:

Mediastinitis (1,212 reports)

Browse all side effects of Paclitaxel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mediastinitis:

Mediastinitis (96 drugs)

Browse all the conditions that are associated with Mediastinitis:

Mediastinitis (230 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on paclitaxel (the active ingredients of Paclitaxel) and Paclitaxel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.