Paclitaxel and Toxic encephalopathy - a phase IV clinical study of FDA data

Summary:

Toxic encephalopathy is reported as a side effect among people who take Paclitaxel (paclitaxel), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Carboplatin, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Toxic encephalopathy when taking Paclitaxel. It is created by eHealthMe based on reports of 85,850 people who have side effects when taking Paclitaxel from the FDA, and is updated regularly.

What is Paclitaxel?

Paclitaxel has active ingredients of paclitaxel. It is often used in breast cancer. eHealthMe is studying from 85,928 Paclitaxel users. Check the latest studies of Paclitaxel.

What is Toxic encephalopathy?

Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances) is found to be associated with 420 drugs and 617 conditions by eHealthMe. Check the latest studies of Toxic encephalopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

85,850 people reported to have side effects when taking Paclitaxel.
Among them, 22 people (0.03%) have Toxic encephalopathy.

Could Paclitaxel cause Toxic encephalopathy?

Among these 22 people:

How long have people been on Paclitaxel when they have Toxic encephalopathy? *

What is the gender of people who have Toxic encephalopathy when taking Paclitaxel? *

female: 95.45 %
male: 4.55 %

What is the age of people who have Toxic encephalopathy when taking Paclitaxel? *

What are other drugs people take besides Paclitaxel? *

What are other side effects people have besides Toxic encephalopathy? *

Memory Loss: 4 people, 18.18%
Personality Change: 4 people, 18.18%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 13.64%
Pneumonia: 2 people, 9.09%
Hypoaesthesia (reduced sense of touch or sensation): 1 person, 4.55%
Hallucinations, Mixed (sensations that appear real but are created by your mind -mixed): 1 person, 4.55%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 4.55%
Generalised Oedema (swelling all over the body): 1 person, 4.55%
General Physical Health Deterioration (weak health status): 1 person, 4.55%
Gamma-Glutamyltransferase Increased: 1 person, 4.55%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 9 people, 40.91%
Infection: 2 people, 9.09%
Productive Cough: 1 person, 4.55%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 4.55%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 4.55%
High Blood Pressure: 1 person, 4.55%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 4.55%
Dyspnea (difficult or laboured breathing): 1 person, 4.55%
Breast Cancer Female: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Paclitaxel and have Toxic encephalopathy?

- Check whether Toxic encephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paclitaxel:

Paclitaxel (85,928 reports)

Browse all side effects of Paclitaxel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Toxic encephalopathy:

Toxic encephalopathy (420 drugs)

Browse all the conditions that are associated with Toxic encephalopathy:

Toxic encephalopathy (617 conditions)

Related publications that referenced our studies

Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on paclitaxel (the active ingredients of Paclitaxel) and Paclitaxel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.