Padcev and Cataract - a phase IV clinical study of FDA data

Summary:

Cataract is reported as a side effect among people who take Padcev (enfortumab vedotin-ejfv), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Fexofenadine Hydrochloride, and have Transitional cell carcinoma.

The phase IV clinical study analyzes which people have Cataract when taking Padcev. It is created by eHealthMe based on reports of 2,536 people who have side effects when taking Padcev from the FDA, and is updated regularly.

What is Padcev?

Padcev has active ingredients of enfortumab vedotin-ejfv. eHealthMe is studying from 2,538 Padcev users. Check the latest studies of Padcev.

What is Cataract?

Cataract (clouding of the lens inside the eye) is found to be associated with 1,892 drugs and 2,133 conditions by eHealthMe. Check the latest studies of Cataract.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 12, 2026

2,536 people reported to have side effects when taking Padcev.
Among them, 12 people (0.47%) have Cataract.

Among these 12 people:

How long have people been on Padcev when they have Cataract? *

What is the gender of people who have Cataract when taking Padcev? *

female: 0.0 %
male: 100 %

What is the age of people who have Cataract when taking Padcev? *

What are other drugs people take besides Padcev? *

Protopic: 2 people, 16.67%
Pemetrexed: 2 people, 16.67%
Nizoral: 2 people, 16.67%
Fluorometholone: 2 people, 16.67%
Fexofenadine Hydrochloride: 2 people, 16.67%
Gemcitabine: 1 person, 8.33%
Carboplatin: 1 person, 8.33%

What are other side effects people have besides Cataract? *

Hair Loss: 3 people, 25.00%
Vision Blurred: 2 people, 16.67%
Skin Discoloration: 2 people, 16.67%
Rashes (redness): 2 people, 16.67%
Ocular Hyperaemia (an abnormally large amount of blood in eye): 2 people, 16.67%
Lacrimation Increased: 2 people, 16.67%
Conjunctivitis (pink eye): 2 people, 16.67%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 2 people, 16.67%
Pain: 1 person, 8.33%
Neuropathy Peripheral (surface nerve damage): 1 person, 8.33%

What are the existing conditions these people have? *

Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 5 people, 41.67%
Ureteric Cancer: 2 people, 16.67%
Ocular Hyperaemia (an abnormally large amount of blood in eye): 2 people, 16.67%
Lacrimation Increased: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Padcev and have Cataract?

- Check whether Cataract is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Padcev:

Padcev (2,538 reports)

Cataract treatments and more:

Cataract (70,565 reports)

Browse all side effects of Padcev:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cataract:

Cataract (1,892 drugs)

Browse all the conditions that are associated with Cataract:

Cataract (2,133 conditions)

Related publications that referenced our studies

Lin SY, Lin CL, Ju SW, Wang IK, Lin CC, Lin CH, Hsu WH, Liang JA, "Increasing risk of cataract in HCV patients receiving anti-HCV therapy: A nationwide cohort study", PloS one, 2017 Mar .
Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
Lin SY, Lin CL, Ju SW, Wang IK, Lin CC, Lin CH, Hsu WH, Liang JA, "Increasing risk of cataract in HCV patients receiving anti-HCV therapy: A nationwide cohort study", PloS one, 2017 Mar .
Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on enfortumab vedotin-ejfv (the active ingredients of Padcev) and Padcev (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.