Padcev and Pain in extremity - a phase IV clinical study of FDA data

Summary:

Pain in extremity is reported as a side effect among people who take Padcev (enfortumab vedotin-ejfv), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Carvedilol, and have Bladder cancer.

The phase IV clinical study analyzes which people have Pain in extremity when taking Padcev. It is created by eHealthMe based on reports of 2,536 people who have side effects when taking Padcev from the FDA, and is updated regularly.

What is Padcev?

Padcev has active ingredients of enfortumab vedotin-ejfv. eHealthMe is studying from 2,538 Padcev users. Check the latest studies of Padcev.

What is Pain in extremity?

Pain in extremity is found to be associated with 3,235 drugs and 4,292 conditions by eHealthMe. Check the latest studies of Pain in extremity.



On Jul, 19, 2026

2,536 people reported to have side effects when taking Padcev.
Among them, 11 people (0.43%) have Pain in extremity.

Could Padcev cause Pain in extremity?

Among these 11 people:

How long have people been on Padcev when they have Pain in extremity? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pain in extremity when taking Padcev? *

  • female: 18.18 %
  • male: 81.82 %

What is the age of people who have Pain in extremity when taking Padcev? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 0.0 %
  • 60+: 88.89 %

What are other drugs people take besides Padcev? *

  1. Omeprazole: 2 people, 18.18%
  2. Livalo: 2 people, 18.18%
  3. Keytruda: 2 people, 18.18%
  4. Hydrochlorothiazide: 2 people, 18.18%
  5. Gemcitabine: 2 people, 18.18%
  6. Ezetimibe: 2 people, 18.18%
  7. Carvedilol: 2 people, 18.18%
  8. Lyrica: 1 person, 9.09%
  9. Carboplatin: 1 person, 9.09%

What are other side effects people have besides Pain in extremity? *

  1. Rashes (redness): 5 people, 45.45%
  2. Fatigue (feeling of tiredness): 5 people, 45.45%
  3. Weakness: 3 people, 27.27%
  4. Unilateral Hydronephrosis (kidney stone that causes obstruction of the ureter): 3 people, 27.27%
  5. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 27.27%
  6. Haematuria (presence of blood in urine): 3 people, 27.27%
  7. Haemoglobin Decreased: 3 people, 27.27%
  8. Skin Ulcer: 3 people, 27.27%
  9. Indigestion: 2 people, 18.18%
  10. Dyspnea Exertional: 2 people, 18.18%

What are the existing conditions these people have? *

  1. Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 4 people, 36.36%
  2. Bladder Cancer: 4 people, 36.36%
  3. Metastases To Liver (cancer spreads to liver): 2 people, 18.18%
  4. Malignant Neoplasm Of Renal Pelvis (cancer tumour of ureter): 1 person, 9.09%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Padcev and have Pain in extremity?

- Check whether Pain in extremity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Padcev:

Pain in extremity treatments and more:

How severe was Pain in extremity and when was it recovered:

Expand to all the drugs that have ingredients of enfortumab vedotin-ejfv:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Padcev:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain in extremity:

Browse all the conditions that are associated with Pain in extremity:


How the study uses the data?

The study uses data from the FDA. It is based on enfortumab vedotin-ejfv (the active ingredients of Padcev) and Padcev (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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