Palladone and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Palladone (hydromorphone hydrochloride), especially for people who are female, 60+ old, also take Oxycontin, and have Pain.

The phase IV clinical study analyzes which people have Stroke when taking Palladone. It is created by eHealthMe based on reports of 2,543 people who have side effects when taking Palladone from the FDA, and is updated regularly.

What is Palladone?

Palladone has active ingredients of hydromorphone hydrochloride. eHealthMe is studying from 2,546 Palladone users. Check the latest studies of Palladone.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,340 drugs and 3,028 conditions by eHealthMe. Check the latest studies of Stroke.

On Jun, 11, 2026

2,543 people reported to have side effects when taking Palladone.
Among them, 24 people (0.94%) have Stroke.

Among these 24 people:

What is the gender of people who have Stroke when taking Palladone? *

female: 54.17 %
male: 45.83 %

What is the age of people who have Stroke when taking Palladone? *

What are other drugs people take besides Palladone? *

Oxycontin: 16 people, 66.67%
Hydrocodone Bitartrate And Acetaminophen: 14 people, 58.33%
Hysingla Er: 13 people, 54.17%
Ms Contin: 12 people, 50.00%
Dhc Plus: 9 people, 37.50%
Dilaudid: 9 people, 37.50%
Butrans: 9 people, 37.50%
Ryzolt: 7 people, 29.17%
Oxycodone Hydrochloride: 4 people, 16.67%
Oxycodone: 4 people, 16.67%

What are other side effects people have besides Stroke? *

Drug Dependence: 17 people, 70.83%
Overdose: 12 people, 50.00%
Dizziness: 10 people, 41.67%
Cardiac Disorder: 10 people, 41.67%
Depression: 9 people, 37.50%
Suicidal Ideation: 8 people, 33.33%
Loss Of Consciousness: 7 people, 29.17%
Learning Disability (difficulty in learning): 7 people, 29.17%
Emotional Distress: 7 people, 29.17%
Erection Problems: 6 people, 25.00%

What are the existing conditions these people have? *

Pain: 14 people, 58.33%
Constipation: 6 people, 25.00%
Heart Attack: 5 people, 20.83%
High Blood Pressure: 4 people, 16.67%
Depression: 4 people, 16.67%
Atherosclerosis (disorder of the arteries): 4 people, 16.67%
Essential Hypertension (primary hypertension): 3 people, 12.50%
Back Pain: 3 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.33%
Osteoporosis (bones weak and more likely to break): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Palladone and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Palladone:

Palladone (2,546 reports)

Stroke treatments and more:

Stroke (334,635 reports)

Browse all side effects of Palladone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,340 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,028 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydromorphone hydrochloride (the active ingredients of Palladone) and Palladone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.