Panthenol and Malaise - a phase IV clinical study of FDA data

Summary:

Malaise is reported as a side effect among people who take Panthenol (pantothenic acid (vitamin b5)), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Azithromycin, and have Crohn's disease.

The phase IV clinical study analyzes which people have Malaise when taking Panthenol. It is created by eHealthMe based on reports of 2,073 people who have side effects when taking Panthenol from the FDA, and is updated regularly.

What is Panthenol?

Panthenol has active ingredients of pantothenic acid (vitamin b5). eHealthMe is studying from 2,079 Panthenol users. Check the latest studies of Panthenol.

What is Malaise?

Malaise (a feeling of general discomfort or uneasiness) is found to be associated with 3,489 drugs and 5,129 conditions by eHealthMe. Check the latest studies of Malaise.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 15, 2026

2,073 people reported to have side effects when taking Panthenol.
Among them, 88 people (4.25%) have Malaise.

Could Panthenol cause Malaise?

Among these 88 people:

How long have people been on Panthenol when they have Malaise? *

  • < 1 month: 66.67 %
  • 1 - 6 months: 16.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 16.67 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Malaise when taking Panthenol? *

  • female: 93.06 %
  • male: 6.94 %

What is the age of people who have Malaise when taking Panthenol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.03 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 18.18 %
  • 50-59: 4.55 %
  • 60+: 74.24 %

What are other drugs people take besides Panthenol? *

  1. Acetaminophen: 49 people, 55.68%
  2. Azithromycin: 49 people, 55.68%
  3. Nicotinamide: 48 people, 54.55%
  4. Prednisone: 48 people, 54.55%
  5. Humira: 47 people, 53.41%
  6. Vitamin D3: 46 people, 52.27%
  7. Pantoprazole: 45 people, 51.14%
  8. Pregabalin: 45 people, 51.14%
  9. Clotrimazole: 44 people, 50.00%
  10. Morphine Sulfate: 44 people, 50.00%

What are other side effects people have besides Malaise? *

  1. Nausea (feeling of having an urge to vomit): 55 people, 62.50%
  2. Pain: 52 people, 59.09%
  3. Indigestion: 52 people, 59.09%
  4. Fever: 51 people, 57.95%
  5. Rashes (redness): 51 people, 57.95%
  6. Weight Decreased: 51 people, 57.95%
  7. Infusion Related Reaction: 51 people, 57.95%
  8. Headache (pain in head): 49 people, 55.68%
  9. Diarrhea: 48 people, 54.55%
  10. Abdominal Pain: 47 people, 53.41%

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 43 people, 48.86%
  2. Allergies: 37 people, 42.05%
  3. Colitis (inflammation of colon): 13 people, 14.77%
  4. Fever: 11 people, 12.50%
  5. Asthma: 10 people, 11.36%
  6. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9 people, 10.23%
  7. Nausea (feeling of having an urge to vomit): 9 people, 10.23%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 9.09%
  9. Insomnia (sleeplessness): 6 people, 6.82%
  10. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Panthenol and have Malaise?

- Check whether Malaise is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Panthenol:

Malaise treatments and more:

How severe was Malaise and when was it recovered:

Expand to all the drugs that have ingredients of pantothenic acid (vitamin b5):

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Panthenol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Malaise:

Browse all the conditions that are associated with Malaise:


How the study uses the data?

The study uses data from the FDA. It is based on pantothenic acid (vitamin b5) (the active ingredients of Panthenol) and Panthenol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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