Pantoprazole and Bradyarrhythmia - a phase IV clinical study of FDA data

Summary:

Bradyarrhythmia is reported as a side effect among people who take Pantoprazole (pantoprazole sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Allopurinol, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Bradyarrhythmia when taking Pantoprazole. It is created by eHealthMe based on reports of 281,696 people who have side effects when taking Pantoprazole from the FDA, and is updated regularly.

What is Pantoprazole?

Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,167 Pantoprazole users. Check the latest studies of Pantoprazole.

What is Bradyarrhythmia?

Bradyarrhythmia (heart slowness) is found to be associated with 272 drugs and 351 conditions by eHealthMe. Check the latest studies of Bradyarrhythmia.

On Aug, 11, 2026

281,696 people reported to have side effects when taking Pantoprazole.
Among them, 70 people (0.02%) have Bradyarrhythmia.

Could Pantoprazole cause Bradyarrhythmia?

Among these 70 people:

How long have people been on Pantoprazole when they have Bradyarrhythmia? *

What is the gender of people who have Bradyarrhythmia when taking Pantoprazole? *

female: 47.76 %
male: 52.24 %

What is the age of people who have Bradyarrhythmia when taking Pantoprazole? *

What are other drugs people take besides Pantoprazole? *

What are other side effects people have besides Bradyarrhythmia? *

Bradycardia (abnormally slow heart action): 16 people, 22.86%
Weakness: 13 people, 18.57%
Arrhythmias (irregular heartbeat): 13 people, 18.57%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 12 people, 17.14%
Atrioventricular Block Second Degree (heart block second degree): 12 people, 17.14%
Sinoatrial Block: 10 people, 14.29%
Confusional State: 9 people, 12.86%
Dyspnea (difficult or laboured breathing): 9 people, 12.86%
Nausea (feeling of having an urge to vomit): 8 people, 11.43%
Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 7 people, 10.00%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 15 people, 21.43%
High Blood Pressure: 11 people, 15.71%
Hepatosplenic Candidiasis (fungal infection in liver and spleen): 10 people, 14.29%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 6 people, 8.57%
Type 2 Diabetes: 6 people, 8.57%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 7.14%
Multiple Myeloma (cancer of the plasma cells): 4 people, 5.71%
Pneumonia: 3 people, 4.29%
Renal Neoplasm (kidney tumour): 2 people, 2.86%
Enlarged Prostate: 2 people, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Pantoprazole and have Bradyarrhythmia?

- Check whether Bradyarrhythmia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pantoprazole:

Pantoprazole (285,167 reports)

Bradyarrhythmia treatments and more:

Bradyarrhythmia (1,986 reports)

Browse all side effects of Pantoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bradyarrhythmia:

Bradyarrhythmia (272 drugs)

Browse all the conditions that are associated with Bradyarrhythmia:

Bradyarrhythmia (351 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pantoprazole sodium (the active ingredients of Pantoprazole) and Pantoprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.