Paroex and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Paroex (chlorhexidine gluconate), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Flagyl, and have Gingivitis ulcerative.

The phase IV clinical study analyzes which people have Insomnia when taking Paroex. It is created by eHealthMe based on reports of 353 people who have side effects when taking Paroex from the FDA, and is updated regularly.

What is Paroex?

Paroex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 356 Paroex users. Check the latest studies of Paroex.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,116 drugs and 5,173 conditions by eHealthMe. Check the latest studies of Insomnia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 26, 2026

353 people reported to have side effects when taking Paroex.
Among them, 16 people (4.53%) have Insomnia.

Among these 16 people:

How long have people been on Paroex when they have Insomnia? *

What is the gender of people who have Insomnia when taking Paroex? *

female: 92.86 %
male: 7.14 %

What is the age of people who have Insomnia when taking Paroex? *

What are other drugs people take besides Paroex? *

Flagyl: 14 people, 87.50%
Zoloft: 9 people, 56.25%
Tegretol: 9 people, 56.25%
Omeprazole: 9 people, 56.25%
Lyrica: 9 people, 56.25%
Cymbalta: 9 people, 56.25%
Amitriptyline Hydrochloride: 9 people, 56.25%
Alprazolam: 9 people, 56.25%
Acetaminophen: 9 people, 56.25%
Sertraline: 8 people, 50.00%

What are other side effects people have besides Insomnia? *

Indigestion: 14 people, 87.50%
Obsessive Thoughts (intrusive thoughts that produce uneasiness, apprehension, fear, or worry): 14 people, 87.50%
Feeling Abnormal: 14 people, 87.50%
Anorectal Disorder: 14 people, 87.50%
Suicide Attempt: 14 people, 87.50%
Dizziness: 14 people, 87.50%
Stress And Anxiety: 14 people, 87.50%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 14 people, 87.50%
Paraplegia (paralysis of the legs and lower body): 14 people, 87.50%
Neuralgia (pain in one or more nerves): 14 people, 87.50%

What are the existing conditions these people have? *

Indigestion: 14 people, 87.50%
Gingivitis Ulcerative (infection of gums with ulcers): 14 people, 87.50%
Partner Stress: 9 people, 56.25%
Abnormal Behavior: 2 people, 12.50%
Gingival Pain (gum pain): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Paroex and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paroex:

Paroex (356 reports)

Insomnia treatments and more:

Insomnia (438,087 reports)

Browse all side effects of Paroex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Insomnia (3,116 drugs)

Browse all the conditions that are associated with Insomnia:

Insomnia (5,173 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Paroex) and Paroex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.