Vitamin c and Red cell distribution width increased - a phase IV clinical study of FDA data

Summary:

Red cell distribution width increased is reported as a side effect among people who take Vitamin c (l-ascorbic acid), especially for people who are female, 60+ old, also take Vitamin D3, and have Nausea.

The phase IV clinical study analyzes which people have Red cell distribution width increased when taking Vitamin c. It is created by eHealthMe based on reports of 89,802 people who have side effects when taking Vitamin c from the FDA, and is updated regularly.

What is Vitamin c?

Vitamin c has active ingredients of l-ascorbic acid. It is often used in immune response. eHealthMe is studying from 92,472 Vitamin c users. Check the latest studies of Vitamin c.

What is Red cell distribution width increased?

Red cell distribution width increased is found to be associated with 604 drugs and 656 conditions by eHealthMe. Check the latest studies of Red cell distribution width increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

89,802 people reported to have side effects when taking Vitamin c.
Among them, 74 people (0.08%) have Red cell distribution width increased.

Could Vitamin c cause Red cell distribution width increased?

Among these 74 people:

What is the gender of people who have Red cell distribution width increased when taking Vitamin c? *

female: 80.88 %
male: 19.12 %

What is the age of people who have Red cell distribution width increased when taking Vitamin c? *

What are other drugs people take besides Vitamin c? *

What are other side effects people have besides Red cell distribution width increased? *

Thrombocytopenia (decrease of platelets in blood): 49 people, 66.22%
Red Blood Cell Count Decreased: 48 people, 64.86%
Fatigue (feeling of tiredness): 45 people, 60.81%
Lymphocyte Count Decreased: 39 people, 52.70%
Haemoglobin Decreased: 37 people, 50.00%
Haematocrit Decreased: 36 people, 48.65%
Weakness: 34 people, 45.95%
White Blood Cell Count Decreased: 33 people, 44.59%
Headache (pain in head): 32 people, 43.24%
Hypoaesthesia (reduced sense of touch or sensation): 32 people, 43.24%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 24 people, 32.43%
Pain: 16 people, 21.62%
Ovarian Cancer (cancer of ovary): 14 people, 18.92%
Cough: 10 people, 13.51%
Constipation: 10 people, 13.51%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 10 people, 13.51%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 9.46%
Stress And Anxiety: 7 people, 9.46%
Joint Swelling: 6 people, 8.11%
Sleep Disorder: 5 people, 6.76%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin c and have Red cell distribution width increased?

- Check whether Red cell distribution width increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin c:

Vitamin c (92,472 reports)

Browse all side effects of Vitamin c:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Red cell distribution width increased:

Red cell distribution width increased (604 drugs)

Browse all the conditions that are associated with Red cell distribution width increased:

Red cell distribution width increased (656 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on l-ascorbic acid (the active ingredients of Vitamin c) and Vitamin c (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.