Paxil and Ear blockage - a phase IV clinical study of FDA data

Summary:

Ear blockage is reported as a side effect among people who take Paxil (paroxetine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lopressor, and have Osteoporosis.

The phase IV clinical study analyzes which people have Ear blockage when taking Paxil. It is created by eHealthMe based on reports of 88,676 people who have side effects when taking Paxil from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,544 Paxil users. Check the latest studies of Paxil.

What is Ear blockage?

Ear blockage is found to be associated with 649 drugs and 948 conditions by eHealthMe. Check the latest studies of Ear blockage.



On Aug, 28, 2025

88,676 people reported to have side effects when taking Paxil.
Among them, 29 people (0.03%) have Ear blockage.

Could Paxil cause Ear blockage?

Among these 29 people:

How long have people been on Paxil when they have Ear blockage? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ear blockage when taking Paxil? *

  • female: 85.71 %
  • male: 14.29 %

What is the age of people who have Ear blockage when taking Paxil? *

  • 0-1: 4 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 4 %
  • 30-39: 8 %
  • 40-49: 12 %
  • 50-59: 8 %
  • 60+: 64 %

What are other drugs people take besides Paxil? *

  1. Lopressor: 18 people, 62.07%
  2. Fosamax: 16 people, 55.17%
  3. Lasix: 16 people, 55.17%
  4. Protonix: 16 people, 55.17%
  5. Coumadin: 15 people, 51.72%
  6. Diovan: 14 people, 48.28%
  7. Premarin: 14 people, 48.28%
  8. Detrol: 13 people, 44.83%
  9. Colace: 12 people, 41.38%
  10. Hydrochlorothiazide: 9 people, 31.03%

What are other side effects people have besides Ear blockage? *

  1. Fall: 17 people, 58.62%
  2. Memory Loss: 15 people, 51.72%
  3. Heart Attack: 15 people, 51.72%
  4. Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 15 people, 51.72%
  5. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 15 people, 51.72%
  6. Asthma: 14 people, 48.28%
  7. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 14 people, 48.28%
  8. Allergic Rhinitis: 14 people, 48.28%
  9. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 14 people, 48.28%
  10. Rectal Prolapse (falling of rectum from normal place): 13 people, 44.83%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 14 people, 48.28%
  2. Pain: 5 people, 17.24%
  3. Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 6.90%
  4. Cough: 2 people, 6.90%
  5. Hypersensitivity: 1 person, 3.45%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.45%
  7. Fungal Infection: 1 person, 3.45%
  8. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 3.45%
  9. Dyspnea (difficult or laboured breathing): 1 person, 3.45%
  10. Dizziness: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Paxil and have Ear blockage?

- Check whether Ear blockage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paxil:

Ear blockage treatments and more:

How severe was Ear blockage and when was it recovered:

Expand to all the drugs that have ingredients of paroxetine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ear blockage:

Browse all the conditions that are associated with Ear blockage:

Drugs similar to Paxil and Ear blockage :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride (the active ingredients of Paxil) and Paxil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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