Paxil and Intercostal retraction - a phase IV clinical study of FDA data

Summary:

Intercostal retraction is reported as a side effect among people who take Paxil (paroxetine hydrochloride), especially for people who are male, 0-1 old, have been taking the drug for 6 - 12 months also take Folic Acid, and have Multiple allergies.

The phase IV clinical study analyzes which people have Intercostal retraction when taking Paxil. It is created by eHealthMe based on reports of 88,676 people who have side effects when taking Paxil from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

What is Intercostal retraction?

Intercostal retraction (inward movement of the muscles between the ribs as a result of reduced pressure in the chest cavity) is found to be associated with 15 drugs and 71 conditions by eHealthMe. Check the latest studies of Intercostal retraction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

88,676 people reported to have side effects when taking Paxil.
Among them, 47 people (0.05%) have Intercostal retraction.

Could Paxil cause Intercostal retraction?

Among these 47 people:

How long have people been on Paxil when they have Intercostal retraction? *

  • < 1 month: 8.7 %
  • 1 - 6 months: 13.04 %
  • 6 - 12 months: 43.48 %
  • 1 - 2 years: 34.78 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Intercostal retraction when taking Paxil? *

  • female: 17.02 %
  • male: 82.98 %

What is the age of people who have Intercostal retraction when taking Paxil? *

  • 0-1: 100 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Paxil? *

  1. Folic Acid: 16 people, 34.04%
  2. Tylenol: 11 people, 23.40%
  3. Depakene: 9 people, 19.15%
  4. Lansoprazole: 8 people, 17.02%
  5. Aleve: 8 people, 17.02%
  6. Amoxicillin: 8 people, 17.02%
  7. Benadryl: 8 people, 17.02%
  8. Naproxen: 8 people, 17.02%
  9. Motrin: 8 people, 17.02%
  10. Macrobid: 8 people, 17.02%

What are other side effects people have besides Intercostal retraction? *

  1. Drug Exposure During Pregnancy: 37 people, 78.72%
  2. Cardiac Murmur (an heart sound in valve abnormality): 30 people, 63.83%
  3. Respiratory Distress (difficulty in breathing): 24 people, 51.06%
  4. Dyspnea (difficult or laboured breathing): 23 people, 48.94%
  5. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 23 people, 48.94%
  6. Coarctation Of The Aorta (narrowing of the part of aorta): 21 people, 44.68%
  7. Enlarged Heart: 19 people, 40.43%
  8. Tachypnea: 19 people, 40.43%
  9. Skin Discoloration - Bluish (bluish colour of skin): 18 people, 38.30%
  10. Persistent Foetal Circulation (baby's blood does not need to pass by the lungs): 16 people, 34.04%

What are the existing conditions these people have? *

  1. Multiple Allergies (allergy to multiple agents): 8 people, 17.02%
  2. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 7 people, 14.89%
  3. Upper Respiratory Tract Infection: 3 people, 6.38%
  4. Pain: 2 people, 4.26%
  5. Nasopharyngitis (inflammation of the nasopharynx): 2 people, 4.26%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.26%
  7. Birth Control: 2 people, 4.26%

* Approximation only. Some reports may have incomplete information.

Do you take Paxil and have Intercostal retraction?

- Check whether Intercostal retraction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paxil:

Intercostal retraction treatments and more:

How severe was Intercostal retraction and when was it recovered:

Expand to all the drugs that have ingredients of paroxetine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intercostal retraction:

Browse all the conditions that are associated with Intercostal retraction:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride (the active ingredients of Paxil) and Paxil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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