Paxil and Metastasis - a phase IV clinical study of FDA data

Summary:

Metastasis is reported as a side effect among people who take Paxil (paroxetine hydrochloride), especially for people who are female, 60+ old, also take Ambien, and have Metastases to bone.

The phase IV clinical study analyzes which people have Metastasis when taking Paxil. It is created by eHealthMe based on reports of 88,676 people who have side effects when taking Paxil from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,547 Paxil users. Check the latest studies of Paxil.

What is Metastasis?

Metastasis (spreadable cancer to other organ from origin) is found to be associated with 528 drugs and 842 conditions by eHealthMe. Check the latest studies of Metastasis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

88,676 people reported to have side effects when taking Paxil.
Among them, 14 people (0.02%) have Metastasis.

Among these 14 people:

What is the gender of people who have Metastasis when taking Paxil? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Metastasis when taking Paxil? *

What are other drugs people take besides Paxil? *

What are other side effects people have besides Metastasis? *

Back Pain: 6 people, 42.86%
Pain In Extremity: 6 people, 42.86%
Rashes (redness): 4 people, 28.57%
Pain: 4 people, 28.57%
High Blood Pressure: 4 people, 28.57%
Chest Pain: 4 people, 28.57%
Anaemia (lack of blood): 4 people, 28.57%
Primary Sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 3 people, 21.43%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 21.43%
Death: 3 people, 21.43%

What are the existing conditions these people have? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
High Blood Pressure: 2 people, 14.29%
Bone Pain: 2 people, 14.29%
Breast Cancer: 2 people, 14.29%
Joint Pain: 2 people, 14.29%
High Blood Cholesterol: 2 people, 14.29%
Heart Attack: 2 people, 14.29%
Metastases To Bone (cancer spreads to bone): 2 people, 14.29%
Headache (pain in head): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Paxil and have Metastasis?

- Check whether Metastasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paxil:

Paxil (92,547 reports)

Metastasis treatments and more:

Metastasis (11,222 reports)

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Metastasis:

Metastasis (528 drugs)

Browse all the conditions that are associated with Metastasis:

Metastasis (842 conditions)

Related publications that referenced our studies

Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride (the active ingredients of Paxil) and Paxil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.