Paxil and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Paxil (paroxetine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Synthroid, and have High blood pressure.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Paxil. It is created by eHealthMe based on reports of 88,676 people who have side effects when taking Paxil from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,544 Paxil users. Check the latest studies of Paxil.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,711 drugs and 1,581 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On Sep, 08, 2025

88,676 people reported to have side effects when taking Paxil.
Among them, 125 people (0.14%) have Thyroid function test abnormal.

Could Paxil cause Thyroid function test abnormal?

Among these 125 people:

How long have people been on Paxil when they have Thyroid function test abnormal? *

What is the gender of people who have Thyroid function test abnormal when taking Paxil? *

female: 77.87 %
male: 22.13 %

What is the age of people who have Thyroid function test abnormal when taking Paxil? *

What are other drugs people take besides Paxil? *

What are other side effects people have besides Thyroid function test abnormal? *

Fatigue (feeling of tiredness): 33 people, 26.40%
Dyspnea Exertional: 28 people, 22.40%
Weight Increased: 25 people, 20.00%
Pain: 24 people, 19.20%
Gout (uric acid crystals building up in the body): 22 people, 17.60%
Back Pain: 21 people, 16.80%
High Blood Pressure: 20 people, 16.00%
Pain In Extremity: 20 people, 16.00%
Rashes (redness): 18 people, 14.40%
Pneumonia: 17 people, 13.60%

What are the existing conditions these people have? *

High Blood Pressure: 26 people, 20.80%
High Blood Cholesterol: 15 people, 12.00%
Osteoporosis (bones weak and more likely to break): 14 people, 11.20%
Joint Pain: 12 people, 9.60%
Panic Disorder: 11 people, 8.80%
Breast Cancer Metastatic: 11 people, 8.80%
Hyperlipidaemia (presence of excess lipids in the blood): 8 people, 6.40%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 6.40%
Cardiac Disorder: 7 people, 5.60%
Sleep Disorder: 7 people, 5.60%

* Approximation only. Some reports may have incomplete information.

Do you take Paxil and have Thyroid function test abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paxil:

Paxil (92,544 reports)

Common Paxil side effects:

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Thyroid function test abnormal:

Browse all the drugs that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,711 drugs)

Common conditions associated with Thyroid function test abnormal:

Rheumatoid arthritis aggravated: 1,901 reports
Ra: 1,897 reports
Multiple sclerosis: 1,590 reports
Blood pressure - high: 1,297 reports
Thyroid disorder: 1,022 reports
Thyroid function test abnormal: 1,020 reports
Under active thyroid: 1,006 reports
Hyperlipidemia: 848 reports
Hypercholesterolaemia: 844 reports
Lipoprotein test: 797 reports

Browse all the conditions that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,581 conditions)

Drugs similar to Paxil and Thyroid function test abnormal :

Related publications that referenced our studies

Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride (the active ingredients of Paxil) and Paxil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.