Paxlovid and Lacrimation increased - a phase IV clinical study of FDA data

Summary:

Lacrimation increased is reported as a side effect among people who take Paxlovid (nirmatrelvir; ritonavir), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have Hypersensitivity.

The phase IV clinical study analyzes which people have Lacrimation increased when taking Paxlovid. It is created by eHealthMe based on reports of 38,421 people who have side effects when taking Paxlovid from the FDA, and is updated regularly.

What is Paxlovid?

Paxlovid has active ingredients of nirmatrelvir; ritonavir. eHealthMe is studying from 38,421 Paxlovid users. Check the latest studies of Paxlovid.

What is Lacrimation increased?

Lacrimation increased is found to be associated with 1,342 drugs and 1,798 conditions by eHealthMe. Check the latest studies of Lacrimation increased.



On Aug, 12, 2026

38,421 people reported to have side effects when taking Paxlovid.
Among them, 49 people (0.13%) have Lacrimation increased.

Could Paxlovid cause Lacrimation increased?

Among these 49 people:

How long have people been on Paxlovid when they have Lacrimation increased? *

  • < 1 month: 95.12 %
  • 1 - 6 months: 2.44 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 2.44 %

What is the gender of people who have Lacrimation increased when taking Paxlovid? *

  • female: 76.6 %
  • male: 23.4 %

What is the age of people who have Lacrimation increased when taking Paxlovid? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 9.52 %
  • 40-49: 14.29 %
  • 50-59: 21.43 %
  • 60+: 54.76 %

What are other drugs people take besides Paxlovid? *

  1. Prednisone: 4 people, 8.16%
  2. Tylenol: 4 people, 8.16%
  3. Synthroid: 4 people, 8.16%
  4. Promacta: 3 people, 6.12%
  5. Magnesium: 3 people, 6.12%
  6. Magnesium Oxide: 3 people, 6.12%
  7. Melatonin: 3 people, 6.12%
  8. Mupirocin: 3 people, 6.12%
  9. Omeprazole: 3 people, 6.12%
  10. Ondansetron: 3 people, 6.12%

What are other side effects people have besides Lacrimation increased? *

  1. Rhinorrhea (watery mucus discharge from the nose): 21 people, 42.86%
  2. Fatigue (feeling of tiredness): 14 people, 28.57%
  3. Headache (pain in head): 11 people, 22.45%
  4. Cough: 11 people, 22.45%
  5. Sneezing: 9 people, 18.37%
  6. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 8 people, 16.33%
  7. Disease Recurrence: 8 people, 16.33%
  8. Oropharyngeal Pain: 7 people, 14.29%
  9. Fever: 6 people, 12.24%
  10. Eye Pruritus (eye itching): 5 people, 10.20%

What are the existing conditions these people have? *

  1. Hypersensitivity: 2 people, 4.08%
  2. Thyroid Diseases: 1 person, 2.04%
  3. Streptococcal Infection: 1 person, 2.04%
  4. Rickets (softening of bones): 1 person, 2.04%
  5. Paranasal Sinus Discomfort: 1 person, 2.04%
  6. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 2.04%
  7. Influenza Like Illness: 1 person, 2.04%
  8. High Blood Pressure: 1 person, 2.04%
  9. High Blood Cholesterol: 1 person, 2.04%
  10. Fungal Infection: 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Paxlovid and have Lacrimation increased?

- Check whether Lacrimation increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paxlovid:

Lacrimation increased treatments and more:

How severe was Lacrimation increased and when was it recovered:

Expand to all the drugs that have ingredients of nirmatrelvir; ritonavir:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paxlovid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lacrimation increased:

Browse all the conditions that are associated with Lacrimation increased:


How the study uses the data?

The study uses data from the FDA. It is based on nirmatrelvir; ritonavir (the active ingredients of Paxlovid) and Paxlovid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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