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Pemetrexed disodium and Anaphylaxis - a phase IV clinical study of FDA data

Summary:

Anaphylaxis is reported as a side effect among people who take Pemetrexed disodium (pemetrexed disodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Keytruda, and have Depression.

The phase IV clinical study analyzes which people have Anaphylaxis when taking Pemetrexed disodium. It is created by eHealthMe based on reports of 4,269 people who have side effects when taking Pemetrexed disodium from the FDA, and is updated regularly.

What is Pemetrexed disodium?

Pemetrexed disodium has active ingredients of pemetrexed disodium. eHealthMe is studying from 4,270 Pemetrexed disodium users. Check the latest studies of Pemetrexed disodium.

What is Anaphylaxis?

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) is found to be associated with 1,935 drugs and 2,858 conditions by eHealthMe. Check the latest studies of Anaphylaxis.

On Aug, 04, 2026

4,269 people reported to have side effects when taking Pemetrexed disodium.
Among them, 25 people (0.59%) have Anaphylaxis.

Could Pemetrexed disodium cause Anaphylaxis?

Among these 25 people:

How long have people been on Pemetrexed disodium when they have Anaphylaxis? *

  • < 1 month: 66.67 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Anaphylaxis when taking Pemetrexed disodium? *

  • female: 60 %
  • male: 40 %

What is the age of people who have Anaphylaxis when taking Pemetrexed disodium? *

  • 0-1: 0.0 %
  • 2-9: 5 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5 %
  • 40-49: 5 %
  • 50-59: 30 %
  • 60+: 55 %

What are other drugs people take besides Pemetrexed disodium? *

  1. Keytruda: 8 people, 32.00%
  2. Ondansetron: 6 people, 24.00%
  3. Carboplatin: 4 people, 16.00%
  4. Dexamethasone: 4 people, 16.00%
  5. Shark Cartilage: 3 people, 12.00%
  6. Ondansetron Hydrochloride: 3 people, 12.00%
  7. Cisplatin: 3 people, 12.00%
  8. Opdivo: 2 people, 8.00%
  9. Cyanocobalamin: 2 people, 8.00%
  10. Fentanyl: 1 person, 4.00%

What are other side effects people have besides Anaphylaxis? *

  1. Cardiotoxicity (damage to the heart muscle): 6 people, 24.00%
  2. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 6 people, 24.00%
  3. Haemodynamic Instability (disturbances in the blood movement in our body): 6 people, 24.00%
  4. Hypersensitivity: 6 people, 24.00%
  5. Sudden Cardiac Death: 5 people, 20.00%
  6. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 5 people, 20.00%
  7. Hepatitis (inflammation of the liver): 4 people, 16.00%
  8. Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 3 people, 12.00%
  9. Loss Of Consciousness: 3 people, 12.00%
  10. Cardiac Arrest: 3 people, 12.00%

What are the existing conditions these people have? *

  1. Pleural Mesothelioma (cancer of the pleura, or the membrane that lines the lungs): 6 people, 24.00%
  2. Pain: 6 people, 24.00%
  3. High Blood Pressure: 6 people, 24.00%
  4. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 6 people, 24.00%
  5. Depression: 6 people, 24.00%
  6. Lung Adenocarcinoma (a form of non-small cell lung cancer): 5 people, 20.00%
  7. Lung Cancer - Non-Small Cell (lung cancer): 4 people, 16.00%
  8. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 3 people, 12.00%
  9. Mesothelioma Malignant (cancer that occurs in the thin layer of cells lining the body's internal organs, known as the mesothelium): 2 people, 8.00%
  10. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Pemetrexed disodium and have Anaphylaxis?

- Check whether Anaphylaxis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pemetrexed disodium:

Anaphylaxis treatments and more:

How severe was Anaphylaxis and when was it recovered:

Expand to all the drugs that have ingredients of pemetrexed disodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pemetrexed disodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anaphylaxis:

Browse all the conditions that are associated with Anaphylaxis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on pemetrexed disodium (the active ingredients of Pemetrexed disodium) and Pemetrexed disodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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