Penicillamine and Malaise - a phase IV clinical study of FDA data

Summary:

Malaise is reported as a side effect among people who take Penicillamine (penicillamine), especially for people who are female, 60+ old, also take Enbrel, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Malaise when taking Penicillamine. It is created by eHealthMe based on reports of 1,329 people who have side effects when taking Penicillamine from the FDA, and is updated regularly.

What is Penicillamine?

Penicillamine has active ingredients of penicillamine. eHealthMe is studying from 1,329 Penicillamine users. Check the latest studies of Penicillamine.

What is Malaise?

Malaise (a feeling of general discomfort or uneasiness) is found to be associated with 3,493 drugs and 5,125 conditions by eHealthMe. Check the latest studies of Malaise.

On Aug, 05, 2026

1,329 people reported to have side effects when taking Penicillamine.
Among them, 18 people (1.35%) have Malaise.

Among these 18 people:

What is the gender of people who have Malaise when taking Penicillamine? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Malaise when taking Penicillamine? *

What are other drugs people take besides Penicillamine? *

What are other side effects people have besides Malaise? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 38.89%
Nausea (feeling of having an urge to vomit): 6 people, 33.33%
Joint Pain: 5 people, 27.78%
Back Pain: 5 people, 27.78%
Peripheral Swelling: 5 people, 27.78%
Joint Stiffness: 5 people, 27.78%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 5 people, 27.78%
Back Injury: 4 people, 22.22%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 4 people, 22.22%
Vasculitis (inflammation of a blood vessel or blood vessels): 4 people, 22.22%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 44.44%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 1 person, 5.56%
Systemic Sclerosis (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 1 person, 5.56%
Skin Ulcer: 1 person, 5.56%
Pain: 1 person, 5.56%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 5.56%
Nausea (feeling of having an urge to vomit): 1 person, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.56%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Penicillamine and have Malaise?

- Check whether Malaise is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Penicillamine:

Penicillamine (1,329 reports)

Malaise treatments and more:

Malaise (529,933 reports)

Browse all side effects of Penicillamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Malaise:

Malaise (3,493 drugs)

Browse all the conditions that are associated with Malaise:

Malaise (5,125 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on penicillamine (the active ingredients of Penicillamine) and Penicillamine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.