Penlac and Syncope - a phase IV clinical study of FDA data

Summary:

Syncope is reported as a side effect among people who take Penlac (ciclopirox), especially for people who are female, 60+ old, also take Colace, and have Constipation.

The phase IV clinical study analyzes which people have Syncope when taking Penlac. It is created by eHealthMe based on reports of 488 people who have side effects when taking Penlac from the FDA, and is updated regularly.

What is Penlac?

Penlac has active ingredients of ciclopirox. eHealthMe is studying from 492 Penlac users. Check the latest studies of Penlac.

What is Syncope?

Syncope (loss of consciousness with an inability to maintain postural tone) is found to be associated with 3,348 drugs and 3,529 conditions by eHealthMe. Check the latest studies of Syncope.

On May, 24, 2026

488 people reported to have side effects when taking Penlac.
Among them, 11 people (2.25%) have Syncope.

Among these 11 people:

What is the gender of people who have Syncope when taking Penlac? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Syncope when taking Penlac? *

What are other drugs people take besides Penlac? *

Colace: 8 people, 72.73%
Avelox: 7 people, 63.64%
Lyrica: 7 people, 63.64%
Esomeprazole Magnesium: 6 people, 54.55%
Levaquin: 6 people, 54.55%
Ativan: 6 people, 54.55%
Aredia: 6 people, 54.55%
Zometa: 6 people, 54.55%
Coenzyme Q10: 6 people, 54.55%
Ergocalciferol: 5 people, 45.45%

What are other side effects people have besides Syncope? *

Pain: 9 people, 81.82%
Stress And Anxiety: 7 people, 63.64%
Weakness: 7 people, 63.64%
Constipation: 7 people, 63.64%
Sinusitis (inflammation of sinus): 7 people, 63.64%
Abdominal Distension: 7 people, 63.64%
Urination - Excessive At Night: 6 people, 54.55%
Decreased Interest: 6 people, 54.55%
Hepatic Lesion: 6 people, 54.55%
Visual Impairment: 6 people, 54.55%

What are the existing conditions these people have? *

Constipation: 7 people, 63.64%
Pain: 5 people, 45.45%
Nausea (feeling of having an urge to vomit): 5 people, 45.45%
Ill-Defined Disorder: 2 people, 18.18%
Bone Disorder: 2 people, 18.18%
Dyspnea (difficult or laboured breathing): 2 people, 18.18%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 18.18%
Multiple Myeloma (cancer of the plasma cells): 2 people, 18.18%
High Blood Pressure: 1 person, 9.09%
High Blood Cholesterol: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Penlac and have Syncope?

- Check whether Syncope is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Penlac:

Penlac (492 reports)

Syncope treatments and more:

Syncope (131,321 reports)

Browse all side effects of Penlac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Syncope:

Syncope (3,348 drugs)

Browse all the conditions that are associated with Syncope:

Syncope (3,529 conditions)

Related publications that referenced our studies

Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .
Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on ciclopirox (the active ingredients of Penlac) and Penlac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.