Pennsaid and Hot flush - a phase IV clinical study of FDA data

Summary:

Hot flush is reported as a side effect among people who take Pennsaid (diclofenac sodium), especially for people who are 60+ old, have been taking the drug for < 1 month also take Aspirin, and have High blood pressure.

The phase IV clinical study analyzes which people have Hot flush when taking Pennsaid. It is created by eHealthMe based on reports of 2,824 people who have side effects when taking Pennsaid from the FDA, and is updated regularly.

What is Pennsaid?

Pennsaid has active ingredients of diclofenac sodium. eHealthMe is studying from 2,849 Pennsaid users. Check the latest studies of Pennsaid.

What is Hot flush?

Hot flush (sudden feelings of heat) is found to be associated with 1,769 drugs and 2,343 conditions by eHealthMe. Check the latest studies of Hot flush.

On Jul, 14, 2026

2,824 people reported to have side effects when taking Pennsaid.
Among them, 12 people (0.42%) have Hot flush.

Among these 12 people:

How long have people been on Pennsaid when they have Hot flush? *

What is the age of people who have Hot flush when taking Pennsaid? *

What are other drugs people take besides Pennsaid? *

Acidophilus: 4 people, 33.33%
Claritin: 4 people, 33.33%
Oxycodone And Acetaminophen: 4 people, 33.33%
Flonase Allergy Relief: 4 people, 33.33%
Evening Primrose Oil: 4 people, 33.33%
Premarin: 4 people, 33.33%
Medrol: 4 people, 33.33%
Revlimid: 4 people, 33.33%
Bactrim: 4 people, 33.33%
Aspirin: 4 people, 33.33%

What are other side effects people have besides Hot flush? *

Rashes (redness): 6 people, 50.00%
Hoarseness Or Changing Voice: 6 people, 50.00%
Night Sweats (sweating in night): 5 people, 41.67%
Fatigue (feeling of tiredness): 5 people, 41.67%
Itching: 5 people, 41.67%
Pain In Extremity: 5 people, 41.67%
Skin Exfoliation (removal of the oldest dead skin cells): 4 people, 33.33%
Fall: 3 people, 25.00%
Headache (pain in head): 3 people, 25.00%
Hyperhidrosis (abnormally increased sweating): 3 people, 25.00%

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 50.00%
Multiple Myeloma (cancer of the plasma cells): 4 people, 33.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 25.00%
Insomnia (sleeplessness): 2 people, 16.67%
Anaemia (lack of blood): 2 people, 16.67%
Calcium Deficiency (lack of calcium): 2 people, 16.67%
Gastric Ulcer (stomach ulcer): 2 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
High Blood Cholesterol: 2 people, 16.67%
Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Pennsaid and have Hot flush?

- Check whether Hot flush is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pennsaid:

Pennsaid (2,849 reports)

Hot flush treatments and more:

Hot flush (91,208 reports)

Browse all side effects of Pennsaid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flush:

Hot flush (1,769 drugs)

Browse all the conditions that are associated with Hot flush:

Hot flush (2,343 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium (the active ingredients of Pennsaid) and Pennsaid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.