Pentoxifylline and Skin blushing/flushing - a phase IV clinical study of FDA data

Summary:

Skin blushing/flushing is reported as a side effect among people who take Pentoxifylline (pentoxifylline), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Niaspan, and have High density lipoprotein decreased.

The phase IV clinical study analyzes which people have Skin blushing/flushing when taking Pentoxifylline. It is created by eHealthMe based on reports of 5,929 people who have side effects when taking Pentoxifylline from the FDA, and is updated regularly.

What is Pentoxifylline?

Pentoxifylline has active ingredients of pentoxifylline. eHealthMe is studying from 5,997 Pentoxifylline users. Check the latest studies of Pentoxifylline.

What is Skin blushing/flushing?

Skin blushing/flushing (a sudden reddening of the face, neck) is found to be associated with 2,009 drugs and 2,936 conditions by eHealthMe. Check the latest studies of Skin blushing/flushing.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

5,929 people reported to have side effects when taking Pentoxifylline.
Among them, 19 people (0.32%) have Skin blushing/flushing.

Could Pentoxifylline cause Skin blushing/flushing?

Among these 19 people:

How long have people been on Pentoxifylline when they have Skin blushing/flushing? *

What is the gender of people who have Skin blushing/flushing when taking Pentoxifylline? *

female: 52.63 %
male: 47.37 %

What is the age of people who have Skin blushing/flushing when taking Pentoxifylline? *

What are other drugs people take besides Pentoxifylline? *

What are other side effects people have besides Skin blushing/flushing? *

Itching: 7 people, 36.84%
Diarrhea: 5 people, 26.32%
Hypotension (abnormally low blood pressure): 4 people, 21.05%
Dizziness: 4 people, 21.05%
Fainting (loss of consciousness and postural tone): 4 people, 21.05%
Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 15.79%
Nausea (feeling of having an urge to vomit): 3 people, 15.79%
Hyperhidrosis (abnormally increased sweating): 3 people, 15.79%
Rashes (redness): 3 people, 15.79%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 15.79%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.53%
High Blood Cholesterol: 2 people, 10.53%
High Density Lipoprotein Decreased: 2 people, 10.53%
Wound Infection: 1 person, 5.26%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 1 person, 5.26%
Blood Pressure Abnormal: 1 person, 5.26%
Cardiovascular Insufficiency (inadequate functioning of heart): 1 person, 5.26%
Chest Pain: 1 person, 5.26%
Depression: 1 person, 5.26%
Diabetes: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Pentoxifylline and have Skin blushing/flushing?

- Check whether Skin blushing/flushing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pentoxifylline:

Pentoxifylline (5,997 reports)

Browse all side effects of Pentoxifylline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin blushing/flushing:

Skin blushing/flushing (2,009 drugs)

Browse all the conditions that are associated with Skin blushing/flushing:

Skin blushing/flushing (2,936 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pentoxifylline (the active ingredients of Pentoxifylline) and Pentoxifylline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.