Pepcid and Icterus - a phase IV clinical study of FDA data

Summary:

Icterus is reported as a side effect among people who take Pepcid (famotidine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zofran, and have Gastritis.

The phase IV clinical study analyzes which people have Icterus when taking Pepcid. It is created by eHealthMe based on reports of 54,527 people who have side effects when taking Pepcid from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,766 Pepcid users. Check the latest studies of Pepcid.

What is Icterus?

Icterus (yellowish pigmentation of the skin) is found to be associated with 2,194 drugs and 2,985 conditions by eHealthMe. Check the latest studies of Icterus.

On Oct, 24, 2025

54,527 people reported to have side effects when taking Pepcid.
Among them, 121 people (0.22%) have Icterus.

Among these 121 people:

How long have people been on Pepcid when they have Icterus? *

What is the gender of people who have Icterus when taking Pepcid? *

female: 47.86 %
male: 52.14 %

What is the age of people who have Icterus when taking Pepcid? *

What are other drugs people take besides Pepcid? *

What are other side effects people have besides Icterus? *

Nausea And Vomiting: 35 people, 28.93%
Fatigue (feeling of tiredness): 29 people, 23.97%
Alanine Aminotransferase Increased: 28 people, 23.14%
Aspartate Aminotransferase Increased: 28 people, 23.14%
Nausea (feeling of having an urge to vomit): 27 people, 22.31%
Anaemia (lack of blood): 25 people, 20.66%
Fever: 24 people, 19.83%
Blood Bilirubin Increased: 24 people, 19.83%
Headache (pain in head): 20 people, 16.53%
Weakness: 19 people, 15.70%

What are the existing conditions these people have? *

Gastritis (inflammation of stomach): 13 people, 10.74%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 9 people, 7.44%
Pain: 8 people, 6.61%
Birth Control: 8 people, 6.61%
Nausea (feeling of having an urge to vomit): 7 people, 5.79%
High Blood Pressure: 6 people, 4.96%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 4.96%
Urinary Tract Infection: 6 people, 4.96%
Stress And Anxiety: 6 people, 4.96%
Pneumonia: 5 people, 4.13%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid and have Icterus?

- Check whether Icterus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pepcid:

Pepcid (55,766 reports)

Icterus treatments and more:

Icterus (33,621 reports)

Browse all side effects of Pepcid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Icterus:

Browse all the drugs that are associated with Icterus:

Icterus (2,194 drugs)

Common conditions associated with Icterus:

High blood pressure: 2,055 reports
Hiv antibody positive: 1,000 reports
Hiv test: 978 reports
Hepatitis c: 954 reports
Pain exacerbated: 856 reports
Alternative medicine - pain relief: 832 reports
Antidepressant therapy: 830 reports
Diabetes mellitus: 676 reports
Diabetes - type 2: 667 reports
Rheumatoid arthritis aggravated: 663 reports

Browse all the conditions that are associated with Icterus:

Icterus (2,985 conditions)

Drugs similar to Pepcid and Icterus :

How the study uses the data?

The study uses data from the FDA. It is based on famotidine (the active ingredients of Pepcid) and Pepcid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.