Pepcid and Liver function test abnormal - a phase IV clinical study of FDA data

Summary:

Liver function test abnormal is reported as a side effect among people who take Pepcid (famotidine), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lasix, and have Pain.

The phase IV clinical study analyzes which people have Liver function test abnormal when taking Pepcid. It is created by eHealthMe based on reports of 54,527 people who have side effects when taking Pepcid from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,766 Pepcid users. Check the latest studies of Pepcid.

What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,549 drugs and 1,943 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.



On Nov, 10, 2025

54,527 people reported to have side effects when taking Pepcid.
Among them, 151 people (0.28%) have Liver function test abnormal.

Could Pepcid cause Liver function test abnormal?

Among these 151 people:

How long have people been on Pepcid when they have Liver function test abnormal? *

  • < 1 month: 20 %
  • 1 - 6 months: 80 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Liver function test abnormal when taking Pepcid? *

  • female: 61.64 %
  • male: 38.36 %

What is the age of people who have Liver function test abnormal when taking Pepcid? *

  • 0-1: 0.79 %
  • 2-9: 4.72 %
  • 10-19: 4.72 %
  • 20-29: 3.15 %
  • 30-39: 8.66 %
  • 40-49: 14.96 %
  • 50-59: 18.9 %
  • 60+: 44.09 %

What are other drugs people take besides Pepcid? *

  1. Lasix: 29 people, 19.21%
  2. Tylenol: 26 people, 17.22%
  3. Benadryl: 26 people, 17.22%
  4. Synthroid: 24 people, 15.89%
  5. Zofran: 23 people, 15.23%
  6. Prednisone: 23 people, 15.23%
  7. Ativan: 20 people, 13.25%
  8. Vioxx: 17 people, 11.26%
  9. Coumadin: 16 people, 10.60%
  10. Aspirin: 16 people, 10.60%

What are other side effects people have besides Liver function test abnormal? *

  1. Nausea (feeling of having an urge to vomit): 36 people, 23.84%
  2. Fatigue (feeling of tiredness): 28 people, 18.54%
  3. Nausea And Vomiting: 26 people, 17.22%
  4. Dyspnea (difficult or laboured breathing): 22 people, 14.57%
  5. Alanine Aminotransferase Increased: 20 people, 13.25%
  6. Diarrhea: 20 people, 13.25%
  7. Weight Decreased: 19 people, 12.58%
  8. Hypotension (abnormally low blood pressure): 19 people, 12.58%
  9. Fever: 18 people, 11.92%
  10. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 18 people, 11.92%

What are the existing conditions these people have? *

  1. Pain: 15 people, 9.93%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 12 people, 7.95%
  3. Meningitis Fungal (fungal inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 7 people, 4.64%
  4. High Blood Pressure: 7 people, 4.64%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 3.97%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 3.97%
  7. Stress And Anxiety: 5 people, 3.31%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 2.65%
  9. Breast Cancer Metastatic: 4 people, 2.65%
  10. Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 2.65%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid and have Liver function test abnormal?

- Check whether Liver function test abnormal is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pepcid:

Liver function test abnormal treatments and more:

How severe was Liver function test abnormal and when was it recovered:

Expand to all the drugs that have ingredients of famotidine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Pepcid side effects:

Browse all side effects of Pepcid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Liver function test abnormal:

Browse all the drugs that are associated with Liver function test abnormal:

Common conditions associated with Liver function test abnormal:

Browse all the conditions that are associated with Liver function test abnormal:

Drugs similar to Pepcid and Liver function test abnormal :


How the study uses the data?

The study uses data from the FDA. It is based on famotidine (the active ingredients of Pepcid) and Pepcid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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