Percocet and Ophthalmoplegia - a phase IV clinical study of FDA data

Summary:

Ophthalmoplegia is reported as a side effect among people who take Percocet (acetaminophen; oxycodone hydrochloride), especially for people who are male, 60+ old, also take Nexium, and have Malignant melanoma.

The phase IV clinical study analyzes which people have Ophthalmoplegia when taking Percocet. It is created by eHealthMe based on reports of 116,194 people who have side effects when taking Percocet from the FDA, and is updated regularly.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

What is Ophthalmoplegia?

Ophthalmoplegia (a paralysis or weakness of one or more of the muscles that control eye movement) is found to be associated with 228 drugs and 362 conditions by eHealthMe. Check the latest studies of Ophthalmoplegia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

116,194 people reported to have side effects when taking Percocet.
Among them, 11 people (0.01%) have Ophthalmoplegia.

Among these 11 people:

What is the gender of people who have Ophthalmoplegia when taking Percocet? *

female: 45.45 %
male: 54.55 %

What is the age of people who have Ophthalmoplegia when taking Percocet? *

What are other drugs people take besides Percocet? *

What are other side effects people have besides Ophthalmoplegia? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 36.36%
Headache (pain in head): 3 people, 27.27%
Visual Acuity Reduced (reduced clearness of vision): 3 people, 27.27%
Blindness Unilateral: 3 people, 27.27%
Blindness: 2 people, 18.18%
Nausea And Vomiting: 2 people, 18.18%
Facial Paralysis (loss of function of face muscle): 1 person, 9.09%
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 1 person, 9.09%
Eye Disorder: 1 person, 9.09%
Fatigue (feeling of tiredness): 1 person, 9.09%

What are the existing conditions these people have? *

Malignant Melanoma (skin cancer rises from melancytes): 3 people, 27.27%
Breast Cancer Metastatic: 2 people, 18.18%
Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 1 person, 9.09%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 9.09%
Nausea (feeling of having an urge to vomit): 1 person, 9.09%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 9.09%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
Gait Disturbance: 1 person, 9.09%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Percocet and have Ophthalmoplegia?

- Check whether Ophthalmoplegia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Percocet:

Percocet (119,838 reports)

Ophthalmoplegia treatments and more:

Ophthalmoplegia (1,747 reports)

How severe was Ophthalmoplegia and when was it recovered:

Ophthalmoplegia in Percocet

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Ophthalmoplegia and drugs with ingredients of acetaminophen; oxycodone hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Percocet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ophthalmoplegia:

Ophthalmoplegia (228 drugs)

Browse all the conditions that are associated with Ophthalmoplegia:

Ophthalmoplegia (362 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Percocet) and Percocet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.