Percocet and Synovial disorder - a phase IV clinical study of FDA data

Summary:

Synovial disorder is reported as a side effect among people who take Percocet (acetaminophen; oxycodone hydrochloride), especially for people who are female, 40-49 old, also take Folic Acid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Synovial disorder when taking Percocet. It is created by eHealthMe based on reports of 116,194 people who have side effects when taking Percocet from the FDA, and is updated regularly.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

What is Synovial disorder?

Synovial disorder (disease of synovial joint) is found to be associated with 147 drugs and 118 conditions by eHealthMe. Check the latest studies of Synovial disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

116,194 people reported to have side effects when taking Percocet.
Among them, 11 people (0.01%) have Synovial disorder.

Among these 11 people:

What is the gender of people who have Synovial disorder when taking Percocet? *

female: 88.89 %
male: 11.11 %

What is the age of people who have Synovial disorder when taking Percocet? *

What are other drugs people take besides Percocet? *

What are other side effects people have besides Synovial disorder? *

Joint Pain: 10 people, 90.91%
Itching: 9 people, 81.82%
Liver Disorder (liver diseases): 9 people, 81.82%
Fibromyalgia (a long-term condition which causes pain all over the body): 9 people, 81.82%
Rashes (redness): 9 people, 81.82%
Infection: 8 people, 72.73%
Joint Swelling: 8 people, 72.73%
Lung Disorder (lung disease): 8 people, 72.73%
Malaise (a feeling of general discomfort or uneasiness): 8 people, 72.73%
Muscle Aches (muscle pain): 8 people, 72.73%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 72.73%
Inflammation: 5 people, 45.45%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 5 people, 45.45%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 36.36%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 36.36%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 9.09%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 9.09%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Percocet and have Synovial disorder?

- Check whether Synovial disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Percocet:

Percocet (119,838 reports)

Synovial disorder treatments and more:

Synovial disorder (602 reports)

How severe was Synovial disorder and when was it recovered:

Synovial disorder in Percocet

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Synovial disorder and drugs with ingredients of acetaminophen; oxycodone hydrochloride (3 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Percocet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Synovial disorder:

Synovial disorder (147 drugs)

Browse all the conditions that are associated with Synovial disorder:

Synovial disorder (118 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Percocet) and Percocet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.