Periactin and Coagulation time prolonged - a phase IV clinical study of FDA data

Summary:

Coagulation time prolonged is reported as a side effect among people who take Periactin (cyproheptadine hydrochloride), especially for people who are female, also take Abacavir, and have Appetite - increased.

The phase IV clinical study analyzes which people have Coagulation time prolonged when taking Periactin. It is created by eHealthMe based on reports of 2,086 people who have side effects when taking Periactin from the FDA, and is updated regularly.

What is Periactin?

Periactin has active ingredients of cyproheptadine hydrochloride. It is often used in migraine. eHealthMe is studying from 2,214 Periactin users. Check the latest studies of Periactin.

What is Coagulation time prolonged?

Coagulation time prolonged is found to be associated with 213 drugs and 404 conditions by eHealthMe. Check the latest studies of Coagulation time prolonged.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

2,086 people reported to have side effects when taking Periactin.
Among them, 18 people (0.86%) have Coagulation time prolonged.

Could Periactin cause Coagulation time prolonged?

Among these 18 people:

What is the gender of people who have Coagulation time prolonged when taking Periactin? *

female: 100 %
male: 0.0 %

What are other drugs people take besides Periactin? *

What are other side effects people have besides Coagulation time prolonged? *

Head Injury: 18 people, 100.00%
Activated Partial Thromboplastin Time Prolonged: 9 people, 50.00%
Alanine Aminotransferase Increased: 8 people, 44.44%
Microcytic Anaemia (a generic term for any type of anaemia characterized by small red blood cells): 7 people, 38.89%
Aspartate Aminotransferase Increased: 6 people, 33.33%
Injury: 5 people, 27.78%
Abdominal Injury: 2 people, 11.11%
Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 2 people, 11.11%
Cd4 Lymphocytes Decreased: 1 person, 5.56%
Blood Amylase Increased: 1 person, 5.56%

What are the existing conditions these people have? *

Appetite - Increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 18 people, 100.00%
Retroviral Infection (viral infection): 15 people, 83.33%
Hiv Infection: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Periactin and have Coagulation time prolonged?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Periactin:

Periactin (2,214 reports)

Browse all side effects of Periactin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coagulation time prolonged:

Coagulation time prolonged (213 drugs)

Browse all the conditions that are associated with Coagulation time prolonged:

Coagulation time prolonged (404 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cyproheptadine hydrochloride (the active ingredients of Periactin) and Periactin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.