Periactin and Heart rate increased - a phase IV clinical study of FDA data

Summary:

Heart rate increased is reported as a side effect among people who take Periactin (cyproheptadine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Reglan, and have Nasal congestion.

The phase IV clinical study analyzes which people have Heart rate increased when taking Periactin. It is created by eHealthMe based on reports of 2,086 people who have side effects when taking Periactin from the FDA, and is updated regularly.

What is Periactin?

Periactin has active ingredients of cyproheptadine hydrochloride. It is often used in migraine. eHealthMe is studying from 2,214 Periactin users. Check the latest studies of Periactin.

What is Heart rate increased?

Heart rate increased is found to be associated with 2,387 drugs and 3,212 conditions by eHealthMe. Check the latest studies of Heart rate increased.

On Jul, 11, 2026

2,086 people reported to have side effects when taking Periactin.
Among them, 32 people (1.53%) have Heart rate increased.

Could Periactin cause Heart rate increased?

Among these 32 people:

How long have people been on Periactin when they have Heart rate increased? *

What is the gender of people who have Heart rate increased when taking Periactin? *

female: 56.25 %
male: 43.75 %

What is the age of people who have Heart rate increased when taking Periactin? *

What are other drugs people take besides Periactin? *

What are other side effects people have besides Heart rate increased? *

Nausea (feeling of having an urge to vomit): 16 people, 50.00%
Hypotension (abnormally low blood pressure): 13 people, 40.62%
Weakness: 12 people, 37.50%
Headache (pain in head): 10 people, 31.25%
Nausea And Vomiting: 10 people, 31.25%
Hyperhidrosis (abnormally increased sweating): 9 people, 28.12%
Chest Pain: 9 people, 28.12%
Dyspnea (difficult or laboured breathing): 8 people, 25.00%
Mouth Haemorrhage (bleeding from mouth): 8 people, 25.00%
Fainting (loss of consciousness and postural tone): 7 people, 21.88%

What are the existing conditions these people have? *

Upper Respiratory Tract Inflammation: 3 people, 9.38%
Pain: 3 people, 9.38%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 9.38%
High Blood Pressure: 2 people, 6.25%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 6.25%
Haematological Malignancy (cancer that affect blood, bone marrow, and lymph nodes): 2 people, 6.25%
Cough: 2 people, 6.25%
Immunodeficiency Disorders: 2 people, 6.25%
Itching: 2 people, 6.25%
Constipation: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Periactin and have Heart rate increased?

- Check whether Heart rate increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Periactin:

Periactin (2,214 reports)

Browse all side effects of Periactin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart rate increased:

Heart rate increased (2,387 drugs)

Browse all the conditions that are associated with Heart rate increased:

Heart rate increased (3,212 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cyproheptadine hydrochloride (the active ingredients of Periactin) and Periactin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.