Pioglitazone and Swallowing difficulty - a phase IV clinical study of FDA data

Summary:

Swallowing difficulty is reported as a side effect among people who take Pioglitazone (pioglitazone hydrochloride), especially for people who are male, 60+ old, also take Metformin, and have High blood pressure.

The phase IV clinical study analyzes which people have Swallowing difficulty when taking Pioglitazone. It is created by eHealthMe based on reports of 12,725 people who have side effects when taking Pioglitazone from the FDA, and is updated regularly.

What is Pioglitazone?

Pioglitazone has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 12,864 Pioglitazone users. Check the latest studies of Pioglitazone.

What is Swallowing difficulty?

Swallowing difficulty is found to be associated with 2,402 drugs and 3,353 conditions by eHealthMe. Check the latest studies of Swallowing difficulty.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

12,725 people reported to have side effects when taking Pioglitazone.
Among them, 72 people (0.57%) have Swallowing difficulty.

Could Pioglitazone cause Swallowing difficulty?

Among these 72 people:

What is the gender of people who have Swallowing difficulty when taking Pioglitazone? *

female: 38.03 %
male: 61.97 %

What is the age of people who have Swallowing difficulty when taking Pioglitazone? *

What are other drugs people take besides Pioglitazone? *

What are other side effects people have besides Swallowing difficulty? *

Fatigue (feeling of tiredness): 23 people, 31.94%
Weakness: 22 people, 30.56%
Dyspnea (difficult or laboured breathing): 19 people, 26.39%
Pain: 18 people, 25.00%
Nausea (feeling of having an urge to vomit): 17 people, 23.61%
Nausea And Vomiting: 15 people, 20.83%
Diarrhea: 15 people, 20.83%
Dehydration (dryness resulting from the removal of water): 15 people, 20.83%
Insomnia (sleeplessness): 14 people, 19.44%
Constipation: 14 people, 19.44%

What are the existing conditions these people have? *

High Blood Pressure: 13 people, 18.06%
Neoplasm Malignant (cancer tumour): 11 people, 15.28%
Angioedema (rapid swelling of the dermis): 8 people, 11.11%
High Blood Cholesterol: 4 people, 5.56%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 4.17%
Cardiac Failure Chronic: 3 people, 4.17%
Insomnia (sleeplessness): 3 people, 4.17%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 2.78%
Heart Rate Increased: 2 people, 2.78%
Ovarian Cancer (cancer of ovary): 2 people, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Pioglitazone and have Swallowing difficulty?

- Check whether Swallowing difficulty is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pioglitazone:

Pioglitazone (12,864 reports)

Browse all side effects of Pioglitazone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Swallowing difficulty:

Swallowing difficulty (2,402 drugs)

Browse all the conditions that are associated with Swallowing difficulty:

Swallowing difficulty (3,353 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pioglitazone hydrochloride (the active ingredients of Pioglitazone) and Pioglitazone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.