Polaramine and Wheezing - a phase IV clinical study of FDA data

Summary:

Wheezing is reported as a side effect among people who take Polaramine (dexchlorpheniramine maleate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Xolair, and have Hypersensitivity.

The phase IV clinical study analyzes which people have Wheezing when taking Polaramine. It is created by eHealthMe based on reports of 10,478 people who have side effects when taking Polaramine from the FDA, and is updated regularly.

What is Polaramine?

Polaramine has active ingredients of dexchlorpheniramine maleate. It is often used in allergic rhinitis. eHealthMe is studying from 10,531 Polaramine users. Check the latest studies of Polaramine.

What is Wheezing?

Wheezing (a high-pitched whistling sound made while you breath) is found to be associated with 1,807 drugs and 2,208 conditions by eHealthMe. Check the latest studies of Wheezing.



On Jul, 28, 2026

10,478 people reported to have side effects when taking Polaramine.
Among them, 37 people (0.35%) have Wheezing.

Could Polaramine cause Wheezing?

Among these 37 people:

How long have people been on Polaramine when they have Wheezing? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Wheezing when taking Polaramine? *

  • female: 70.27 %
  • male: 29.73 %

What is the age of people who have Wheezing when taking Polaramine? *

  • 0-1: 2.78 %
  • 2-9: 11.11 %
  • 10-19: 2.78 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 2.78 %
  • 50-59: 8.33 %
  • 60+: 72.22 %

What are other drugs people take besides Polaramine? *

  1. Xolair: 22 people, 59.46%
  2. Symbicort: 11 people, 29.73%
  3. Aldurazyme: 4 people, 10.81%
  4. Solu-Cortef: 3 people, 8.11%
  5. Amoxicillin: 3 people, 8.11%
  6. Gliclazide: 2 people, 5.41%
  7. Budesonide: 2 people, 5.41%
  8. Albuterol: 2 people, 5.41%
  9. Glycopyrrolate: 2 people, 5.41%
  10. Simvastatin: 2 people, 5.41%

What are other side effects people have besides Wheezing? *

  1. Dyspnea (difficult or laboured breathing): 31 people, 83.78%
  2. Hypersensitivity: 25 people, 67.57%
  3. Malaise (a feeling of general discomfort or uneasiness): 23 people, 62.16%
  4. Abdominal Pain Upper: 22 people, 59.46%
  5. Chest Pain: 22 people, 59.46%
  6. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 21 people, 56.76%
  7. Cough: 21 people, 56.76%
  8. Feeling Abnormal: 21 people, 56.76%
  9. Asthma: 21 people, 56.76%
  10. Sneezing: 21 people, 56.76%

What are the existing conditions these people have? *

  1. Asthma: 21 people, 56.76%
  2. Hypersensitivity: 21 people, 56.76%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 20 people, 54.05%
  4. Diabetes: 20 people, 54.05%
  5. Blood Pressure Abnormal: 15 people, 40.54%
  6. Gastric Perforation (hole in stomach): 5 people, 13.51%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 2.70%
  8. Breast Cancer: 1 person, 2.70%
  9. Constipation: 1 person, 2.70%
  10. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Polaramine and have Wheezing?

- Check whether Wheezing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Polaramine:

Wheezing treatments and more:

How severe was Wheezing and when was it recovered:

Expand to all the drugs that have ingredients of dexchlorpheniramine maleate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Polaramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Wheezing:

Browse all the conditions that are associated with Wheezing:


How the study uses the data?

The study uses data from the FDA. It is based on dexchlorpheniramine maleate (the active ingredients of Polaramine) and Polaramine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: