Prednisolone and Areflexia - a phase IV clinical study of FDA data

Summary:

Areflexia is reported as a side effect among people who take Prednisolone (prednisolone), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Areflexia when taking Prednisolone. It is created by eHealthMe based on reports of 211,370 people who have side effects when taking Prednisolone from the FDA, and is updated regularly.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

What is Areflexia?

Areflexia (absence of a reflex) is found to be associated with 425 drugs and 728 conditions by eHealthMe. Check the latest studies of Areflexia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

211,370 people reported to have side effects when taking Prednisolone.
Among them, 99 people (0.05%) have Areflexia.

Among these 99 people:

How long have people been on Prednisolone when they have Areflexia? *

What is the gender of people who have Areflexia when taking Prednisolone? *

female: 32.98 %
male: 67.02 %

What is the age of people who have Areflexia when taking Prednisolone? *

What are other drugs people take besides Prednisolone? *

Cyclophosphamide: 16 people, 16.16%
Methotrexate: 15 people, 15.15%
Mycophenolate Mofetil: 12 people, 12.12%
Methylprednisolone: 11 people, 11.11%
Cyclosporine: 10 people, 10.10%
Acyclovir: 8 people, 8.08%
Tacrolimus: 7 people, 7.07%
Azithromycin: 7 people, 7.07%
Fluconazole: 6 people, 6.06%
Lasix: 6 people, 6.06%

What are other side effects people have besides Areflexia? *

Weakness: 45 people, 45.45%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 21 people, 21.21%
Dyspnea (difficult or laboured breathing): 17 people, 17.17%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 16 people, 16.16%
Fever: 15 people, 15.15%
Movement - Uncoordinated: 13 people, 13.13%
Hyporeflexia (a condition of below normal or absent reflexes): 12 people, 12.12%
Muscle Function Loss: 12 people, 12.12%
Diarrhea: 12 people, 12.12%
Dizziness: 12 people, 12.12%

What are the existing conditions these people have? *

Immunodeficiency Disorders: 10 people, 10.10%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 9 people, 9.09%
Arrhythmias (irregular heartbeat): 7 people, 7.07%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 7 people, 7.07%
Plasmablastic Lymphoma (aggressive b-cell cancer occurring mainly in the jaws and oral cavity): 5 people, 5.05%
Spinal Muscular Atrophy (wasting of spinal muscles): 4 people, 4.04%
Hiv Infection: 3 people, 3.03%
Gouty Arthritis (joint inflammation with crystal formation): 3 people, 3.03%
High Blood Cholesterol: 3 people, 3.03%
Osteoporosis (bones weak and more likely to break): 3 people, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisolone and have Areflexia?

- Check whether Areflexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prednisolone:

Prednisolone (212,675 reports)

Areflexia treatments and more:

Areflexia (3,364 reports)

Browse all side effects of Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Areflexia:

Areflexia (425 drugs)

Browse all the conditions that are associated with Areflexia:

Areflexia (728 conditions)

Related publications that referenced our studies

Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .
Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on prednisolone (the active ingredients of Prednisolone) and Prednisolone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.