Prednisolone and Prothrombin level decreased - a phase IV clinical study of FDA data

Summary:

Prothrombin level decreased is reported as a side effect among people who take Prednisolone (prednisolone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Furosemide, and have Deep venous thrombosis.

The phase IV clinical study analyzes which people have Prothrombin level decreased when taking Prednisolone. It is created by eHealthMe based on reports of 211,370 people who have side effects when taking Prednisolone from the FDA, and is updated regularly.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

What is Prothrombin level decreased?

Prothrombin level decreased is found to be associated with 202 drugs and 466 conditions by eHealthMe. Check the latest studies of Prothrombin level decreased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

211,370 people reported to have side effects when taking Prednisolone.
Among them, 35 people (0.02%) have Prothrombin level decreased.

Could Prednisolone cause Prothrombin level decreased?

Among these 35 people:

How long have people been on Prednisolone when they have Prothrombin level decreased? *

What is the gender of people who have Prothrombin level decreased when taking Prednisolone? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Prothrombin level decreased when taking Prednisolone? *

What are other drugs people take besides Prednisolone? *

What are other side effects people have besides Prothrombin level decreased? *

International Normalised Ratio Increased: 8 people, 22.86%
Heart Disease: 5 people, 14.29%
Haemoglobin Decreased: 5 people, 14.29%
Hypotension (abnormally low blood pressure): 5 people, 14.29%
Hepatic Failure (liver failure): 5 people, 14.29%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 4 people, 11.43%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 4 people, 11.43%
Blood Bilirubin Increased: 4 people, 11.43%
Thrombocytopenia (decrease of platelets in blood): 4 people, 11.43%
Alanine Aminotransferase Increased: 4 people, 11.43%

What are the existing conditions these people have? *

Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 11.43%
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 2 people, 5.71%
Prostate Cancer: 1 person, 2.86%
Pain: 1 person, 2.86%
Fever: 1 person, 2.86%
Bronchitis Acute (acute inflammation of the mucous membrane in the bronchial tubes): 1 person, 2.86%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 2.86%
Autoimmune Hepatitis: 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisolone and have Prothrombin level decreased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prednisolone:

Prednisolone (212,675 reports)

Browse all side effects of Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Prothrombin level decreased:

Prothrombin level decreased (202 drugs)

Browse all the conditions that are associated with Prothrombin level decreased:

Prothrombin level decreased (466 conditions)

Related publications that referenced our studies

Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .
Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on prednisolone (the active ingredients of Prednisolone) and Prednisolone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.