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Prednisone and Enzyme abnormality - a phase IV clinical study of FDA data

Summary:

Enzyme abnormality is reported as a side effect among people who take Prednisone (prednisone), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Enbrel, and have Crohn's disease.

The phase IV clinical study analyzes which people have Enzyme abnormality when taking Prednisone. It is created by eHealthMe based on reports of 628,814 people who have side effects when taking Prednisone from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Enzyme abnormality?

Enzyme abnormality is found to be associated with 109 drugs and 337 conditions by eHealthMe. Check the latest studies of Enzyme abnormality.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

628,814 people reported to have side effects when taking Prednisone.
Among them, 61 people (0.01%) have Enzyme abnormality.

Could Prednisone cause Enzyme abnormality?

Among these 61 people:

How long have people been on Prednisone when they have Enzyme abnormality? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Enzyme abnormality when taking Prednisone? *

  • female: 47.37 %
  • male: 52.63 %

What is the age of people who have Enzyme abnormality when taking Prednisone? *

  • 0-1: 3.85 %
  • 2-9: 5.77 %
  • 10-19: 1.92 %
  • 20-29: 7.69 %
  • 30-39: 11.54 %
  • 40-49: 5.77 %
  • 50-59: 9.62 %
  • 60+: 53.85 %

What are other drugs people take besides Prednisone? *

  1. Enbrel: 24 people, 39.34%
  2. Methotrexate: 20 people, 32.79%
  3. Humira: 20 people, 32.79%
  4. Azathioprine: 14 people, 22.95%
  5. Sulfasalazine: 13 people, 21.31%
  6. Leflunomide: 13 people, 21.31%
  7. Orencia: 13 people, 21.31%
  8. Hydroxychloroquine Sulfate: 12 people, 19.67%
  9. Allegra: 7 people, 11.48%
  10. Spinraza: 5 people, 8.20%

What are other side effects people have besides Enzyme abnormality? *

  1. Heart Attack: 23 people, 37.70%
  2. Drug Ineffective: 22 people, 36.07%
  3. Injection Site Reaction: 18 people, 29.51%
  4. Hepatotoxicity (chemical-driven liver damage): 13 people, 21.31%
  5. Rashes (redness): 13 people, 21.31%
  6. Pain: 13 people, 21.31%
  7. Food Intolerance (inability to have food): 13 people, 21.31%
  8. Indigestion: 13 people, 21.31%
  9. Weight Decreased: 12 people, 19.67%
  10. Heart Rate Decreased: 7 people, 11.48%

What are the existing conditions these people have? *

  1. Respiratory Distress (difficulty in breathing): 5 people, 8.20%
  2. Spinal Muscular Atrophy (wasting of spinal muscles): 5 people, 8.20%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 8.20%
  4. Ill-Defined Disorder: 2 people, 3.28%
  5. Osteoporosis (bones weak and more likely to break): 2 people, 3.28%
  6. Rickets (softening of bones): 2 people, 3.28%
  7. High Blood Pressure: 2 people, 3.28%
  8. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 3.28%
  9. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 3.28%
  10. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 1.64%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisone and have Enzyme abnormality?

- Check whether Enzyme abnormality is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prednisone:

Enzyme abnormality treatments and more:

How severe was Enzyme abnormality and when was it recovered:

Expand to all the drugs that have ingredients of prednisone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prednisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enzyme abnormality:

Browse all the conditions that are associated with Enzyme abnormality:

How the study uses the data?

The study uses data from the FDA. It is based on prednisone (the active ingredients of Prednisone) and Prednisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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