Prednisone and Splenic rupture - a phase IV clinical study of FDA data

Summary:

Splenic rupture is reported as a side effect among people who take Prednisone (prednisone), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have Osteoporosis.

The phase IV clinical study analyzes which people have Splenic rupture when taking Prednisone. It is created by eHealthMe based on reports of 628,814 people who have side effects when taking Prednisone from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Splenic rupture?

Splenic rupture is found to be associated with 211 drugs and 375 conditions by eHealthMe. Check the latest studies of Splenic rupture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

628,814 people reported to have side effects when taking Prednisone.
Among them, 71 people (0.01%) have Splenic rupture.

Among these 71 people:

How long have people been on Prednisone when they have Splenic rupture? *

What is the gender of people who have Splenic rupture when taking Prednisone? *

female: 48.48 %
male: 51.52 %

What is the age of people who have Splenic rupture when taking Prednisone? *

What are other drugs people take besides Prednisone? *

What are other side effects people have besides Splenic rupture? *

Rib Fracture: 16 people, 22.54%
Diarrhea: 14 people, 19.72%
Fall: 14 people, 19.72%
Pain: 10 people, 14.08%
Cough: 9 people, 12.68%
Fungal Infection: 8 people, 11.27%
Gastric Ulcer (stomach ulcer): 8 people, 11.27%
Anaemia (lack of blood): 8 people, 11.27%
Pulmonary Embolism (blockage of the main artery of the lung): 8 people, 11.27%
Pulmonary Mass: 8 people, 11.27%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 8 people, 11.27%
High Blood Pressure: 7 people, 9.86%
Burkitt Lymphoma (cancer of the lymphatic system): 7 people, 9.86%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 9.86%
Fluid Imbalance (imbalance of fluid in body in intake and fluid lost): 5 people, 7.04%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 7.04%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 7.04%
Pain: 4 people, 5.63%
Depression: 3 people, 4.23%
Multiple Myeloma (cancer of the plasma cells): 3 people, 4.23%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisone and have Splenic rupture?

- Check whether Splenic rupture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prednisone:

Prednisone (636,827 reports)

Splenic rupture treatments and more:

Splenic rupture (2,042 reports)

Browse all side effects of Prednisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Splenic rupture:

Splenic rupture (211 drugs)

Browse all the conditions that are associated with Splenic rupture:

Splenic rupture (375 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on prednisone (the active ingredients of Prednisone) and Prednisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.